Masses left behind by healed tissue after a fracture or by certain diseases such as bone tumors are called skeletal masses. The skeletal system, like other organs, can develop tumors from any tissue component or metastatic lesions from other organs. Tumors that invade the bone can occur in the bone cells, the hematopoietic component of the bone, the cartilage, and the fibrous or synovial component. Other tumors may arise from the muscles and nerves, blood vessels, and fatty tissue of the bone. Bone lumps may not be felt at first, but when the lump is larger, there may be swelling and pressure pain. If the tumor is located in epiphysis, it can be located in stem bone epiphysis, long bone or flat bone; chondroblastoma should be considered as the first tumor in adolescent epiphysis, while giant cell tumor of bone should be considered as the tumor in adult epiphysis. Histological examination: It is considered to be a diagnostic method with the highest accuracy rate. CT and MRI: It can detect the diseased tissue earlier and has a high accuracy rate. Pathological tissue biopsy: 1.needle sampling, the success rate of which is 80-90%. 2.Excisional sampling of the affected area for examination. 3.Excision or scraping pathological examination: Histopathological examination is performed by pathologists according to the pathological changes of the sectioned tissues for the final correct diagnosis. Bone imaging: Bone imaging can diagnose bone tumor and bone metastasis 3-6 months earlier than X-ray examination, but it should be noted that this method is highly sensitive and low specificity.