1, in principle, elderly people over 60 years old, with severe bone destruction on the X-ray of the knee joint, significant pain, standing or walking dysfunction due to deformity and/or twinning and instability of the joint, are the surgical indications for artificial knee arthroplasty; 2, the purpose of the surgery is, firstly, to relieve pain, and secondly, to improve the stability and mobility of the knee joint. The indications for surgery are determined according to the patient’s condition, age, occupation, weight, mental status, etc.; 3. The late stage of primary osteoarthropathy, rheumatoid arthritis, traumatic arthritis, and some other non-septic arthropathies; 4. Male patients with osteoarthritis at the age of 40-60 years old are suitable for osteotomies or fusion of joints if they must be engaged in physical labor. The same age of patients with rheumatoid arthritis, due to pain and deformity and impaired activity, in order to improve the quality of life, is also the surgical indications for artificial knee replacement; 5, distal femur or proximal tibia bone tumor, there are conditions for limb preservation, can be made after the tumor segment resection, with a special prosthesis for artificial knee arthroplasty.