Neonatal dacryocystitis is caused by unopened lacrimal ducts at birth and presents with lacrimation and increased discharge shortly after birth. In typical cases, mucus or pus can be seen when pressure is applied to the lacrimal sac at the root of the nose in the corner of the large eye. Due to prolonged tear irritation, the child may develop periocular skin eczema, combined with conjunctivitis and even keratitis. In some cases, acute inflammation of the lacrimal sac can occur, with redness, hardness and pain in the skin of the lacrimal sac area, which can lead to orbital cellulitis or even life-threatening intracranial infections in severe cases. Therefore, neonatal dacryocystitis should be treated as early as possible. If a child has increased tearing and discharge after birth, the lacrimal sac area can be massaged within 3 months, and those with purulent discharge need local antibiotic eye drops and ointment. In a small number of children, pressure on the lacrimal sac can open up the membranous obstruction and make it heal spontaneously. For those who still have lacrimation and discharge after the above treatment, outpatient lacrimal flushing and lacrimal duct exploration can be actively performed after 3 months. More than 90% of the children can be cured after one lacrimal duct irrigation. Children with multiple lacrimal flushes and late treatment often require repeated lacrimal tract exploration due to long local inflammation and significant lacrimal tract damage. For children who do not heal after 2 lacrimal tract explorations, lacrimal intubation may be an option.