Patients with advanced bowel cancer will also experience significant pain because the development of tumor will lead to peritoneal metastasis as well as liver metastasis, which will also be secondary to the formation of large amount of ascites, and patients will have significant abdominal pain and abdominal distension, inducing nausea and vomiting. The patient may also be prone to spontaneous peritonitis, which may manifest as fever. Another thing is that the tumor will develop distant metastases, such as lung tissue, cranial metastases, vertebral metastases, and metastases to the rib cage, so they will all manifest as pain. In this case, if the condition allows, pain relief drugs can be given appropriately, including oral morphine tablets, or intramuscular injection of diazoxide and morphine hydrochloride injection, etc. If the tumor develops into intestinal obstruction, the patient will also have obvious pain. If necessary, abdominal wall fistula surgery or gastrointestinal decompression can be performed, and intravenous nutritional support and symptomatic treatment should also be paid attention to.