With standardized treatment, most patients can become significantly less infectious in about 2 weeks and are no longer infectious after about 2 months of treatment. Active tuberculosis is more infectious and patients need early, regular, full, appropriate and combined anti-tuberculosis treatment. Usually, after 2 months of intensive treatment, if the sputum test is negative and the lung lesions are better absorbed than before, then the patient is no longer infectious. In a few patients, drug-resistant tuberculosis develops due to the lack of standardized anti-tuberculosis treatment, which is relatively more infectious and difficult to treat. It may usually take more than half a year or even 1-2 years of treatment to ensure that they are not infectious. If a patient with drug-resistant bacteria is treated with anti-tuberculosis therapy and the sputum is negative for Mycobacterium tuberculosis more than three times, it means that the infectiousness is significantly reduced, but the possibility of infectiousness cannot be completely excluded. In addition, patients should pay attention to strengthening nutrition during the anti-tuberculosis medication period, while regularly testing liver function and kidney function, and reviewing chest CT or chest X-ray to assess the efficacy of treatment.