Primary Parkinson’s disease has a progressive course, and the Hoehn-Yahr scale [1] is generally used to assess the progression of the patient’s disease. In the early stages of the disease, levodopa drugs are very effective, even creating a “honeymoon period” for the drugs. However, as the disease progresses, usually at stages 2.5-4 (see the following chart for staging), the duration of the disease is 5 or 6 years old, or at least 4-5 years old, and the efficacy of the drug gradually begins to decline; at the same time, side effects of the drug begin to appear, such as the switching phenomenon and end-of-dose effects, similar to the “seven-year itch”. This is an important sign for the surgical installation of a brain pacemaker (DBS), which can compensate for the lack of drug efficacy at this time. Although most cases abroad have reported that early installation of a pacemaker can lead to good treatment results. However, for domestic patients, due to economic conditions or health insurance policies, it is recommended that Parkinson’s patients should have a brain pacemaker installed when they reach stage 2.5~4. However, some patients are often reluctant to undergo surgery when the efficacy of their medication decreases and side effects begin to appear, thinking that the medication will last for a period of time, so that the disease becomes more and more severe and the symptoms are increasingly uncontrollable by the medication. By this time, the disease may have exceeded stage 4, and although surgery can improve some symptoms, the effect is definitely not as effective as when the surgery was performed in time, which is half the effort. If the patient has reached stage 5 Parkinson’s, this advanced stage is not suitable for a pacemaker. Parkinson’s disease is a movement disorder that occurs in the elderly, which means that the patient has less movement or cannot control his or her physical behavior. Generally speaking, elderly people can take care of themselves and go out for a walk without any problems; however, in the middle and late stages of Parkinson’s disease, patients are often unable to get up and move around, are bedridden for a long time or have difficulty moving around, which will cause muscle atrophy, as well as swallowing difficulties, respiratory dysfunction, kidney dysfunction and diabetes. Therefore, the patient’s heart and lung function, liver and kidney function, etc. should be evaluated before surgery, otherwise the patient will not be able to go to the operating table if he or she does not pass the basic physical condition. After passing the comprehensive assessment, surgery is possible; if these complications are very serious, the risk of surgery will be greatly increased.