Patient: Examination and laboratory tests: I found a thickened gland in the upper quadrant of the left breast with hypoechogenicity and dense distribution of dotted strong echogenicity with no significant abnormal blood flow signal. The diagnosis was mammary gland hyperplasia with calcification. Treatment: No treatment was performed and no targeted medication was used, only prolotherapy pills were taken. Medical history: In December 2012, a physical examination revealed pitting strong echogenicity in both mammary glands, with the left breast being the most prominent. I would like to consult an expert on how I should proceed with this situation, our doctor here told me to do a mammogram again to confirm that the calcification is benign or malignant, I really do not understand what is going on with this disease, please advise. Breast cysts are disorders caused by endocrine disorders. Women from the age of 30, despite being in the prime of youth, the gland has begun to undergo degenerative changes, so middle-aged and older women are prone to cysts. The best way to examine cysts is ultrasound. Cysts are usually not harmful to the body, so most small cysts do not require treatment, and only a few larger cysts, or cysts that cannot be excluded from tumors, require further Only a few larger cysts, or cysts that cannot be excluded as tumors, require further diagnosis and treatment. There are many reasons to find calcification foci in the breast, such as breastfeeding, inflammation, aging, etc.; these benign calcifications are usually coarse; however, it should be noted that malignant tumors can show calcification in early stage, but this kind of calcification has its own morphological characteristics, usually mud-like fine calcification, and can only be found by mammogram, which requires careful identification by professional doctors. If the diagnosis is not clear, the lesion should be removed for pathological examination.