High-frequency thermotherapy is a method to treat tumor by endogenous thermal effect of high-frequency oscillating electromagnetic field, that is, to use the relevant physical energy to produce thermal effect by precipitation in tissues, so that the temperature of tumor tissues rises to the effective treatment temperature (40-44℃) and maintains for a period of time, causing tumor cell growth and death, without damaging normal cells. Its biggest advantage is that it is non-invasive, has little side effects, can effectively kill tumor cells, relieve patients’ pain, treat cancerous thoracic ascites and improve patients’ quality of life. This treatment is the fifth major treatment internationally after surgery, radiotherapy, chemotherapy and immunotherapy. 1. Heat therapy combined with chemotherapy can enhance the effect of killing tumors. First of all, heat therapy promotes the drugs to enter tumor cells, and it is a prerequisite for the drugs to reach a certain effective drug concentration in tumor cells. Furthermore, heat therapy promotes drug-induced apoptosis of tumor cells. Many chemotherapy drugs can eventually induce apoptosis through different mechanisms, and heat therapy can promote this process. In addition, heat therapy is easy to reach a higher temperature in the central part of tumor tissue, and heat therapy is more likely to induce apoptosis in the acidic environment of the central part. 2.In addition to the direct killing of tumor cells, high-frequency thermotherapy can enhance the effect of radiation therapy on cells and overcome the defects of both, playing the role of complementary advantages and synergistic sensitization. 3.High-frequency thermotherapy combined with external application of traditional Chinese medicine for the treatment of cancer pain and thoracic ascites. High-frequency thermotherapy method is the application of high-frequency electromagnetic field, using the human body and air as the medium of heating between two electrodes, which produces a kind of high-frequency oscillation in the deep tissues of the human body. This high-frequency electromagnetic field acts on the human body, and its energy is absorbed by the tissues, transformed into heat, and increases the tissue temperature, which can promote blood and lymphatic circulation, etc., enhance the phagocytosis of local white blood cells, inhibit bacterial growth, and achieve anti-inflammatory, swelling, pain relief, and promote the absorption of pleural fluid. Elevated temperature can enhance the permeability of the cell membrane. Combined with the external application of traditional Chinese medicine, the change of cell membrane permeability increases the absorption and penetration of the drug by the tissue, thus enhancing the therapeutic effect. Heating can also increase the concentration and reaction speed of intracellular drugs to achieve the purpose of enhancing the efficacy of medicine. Extracorporeal high-frequency treatment is effective, has no obvious side effects, has a wide range of application, and can benefit more patients when combined with radiotherapy and traditional Chinese medicine treatment.