From February 1990 to December 1995, the author treated 58 cases of facial pigmentation in women with evidence-based treatment, which are reported below.1. Clinical data Among the 58 cases in this group, 55 cases were from outpatient clinics, 3 cases were hospitalized, the youngest age was 24 years old, the oldest was 50 years old, the average age was 30.2±7.66 years old, the shortest duration of the disease was 1.5 years, the longest was 12 years, the average duration of the disease was 6.67±4.25 years. The shortest duration of disease was 1.5 years, the longest was 12 years, and the average duration of disease was 6.67±4.25 years. Cao Yingxiang, respiratory specialist of Jinan Hospital of Traditional Chinese Medicine 2. Treatment 2.1 Heart Qi deficiency, stagnant veins and veins type 18 cases, evidence of facial pigmentation, mostly seen under the que (nose root) or forehead, dull color, palpitations and palpitations, chest tightness and shortness of breath, in case of exertion, the tongue is light with white coating and sunken pulse. Treatment: Nourishing the heart and tranquilizing the mind, resolving blood stasis and promoting circulation. Given in Formula 1: Radix Codonopsis Pilosulae, Radix Astragali, Poria, Radix Angelicae Sinensis, Rhizoma Chuanxiong, Radix Paeoniae Alba, Rhizoma Polygonati, Radix Polygonati, Radix Cinnamomi, Radix et Rhizoma Glycyrrhizae, Radix Panax quinquefolium. Liver depression and qi stagnation, the pulse is not smooth type 16 cases, the evidence is seen in the facial pigmentation seen in the nose under the eyes, the color of purple, blue and gray face, two hypochondriac pain, menstrual irregularities, menstrual breast swelling, menstruation purple or blood clots, or dysmenorrhea, depression and irritability, the tongue is dark red with thin white or yellow coating, the pulse string. Treatment: Relieving depression in the liver, regulating Qi and activating Blood circulation, resolving blood stasis and promoting circulation. Given in Formula 2: Radix Bupleurum, fried aromatic herb, Radix Angelicae Sinensis, Chuanxiong, red spoon, fried peach kernel, safflower, cinnamon stick, cicada molasses, soapberry, licorice. Kidney essence deficiency, color floating in appearance 24 cases, evidence of facial pigmentation mostly seen in the chin, dark color, dull face, lumbar pain and knee weakness, menstruation less or closed, less sleep and more dreams, light tongue with white moss or less moss, sunken and weak pulse. Treatment: Tonifying the kidney essence, nourishing blood and moistening dryness. Recipe No.3: Radix Rehmanniae Praeparata, Radix Rehmanniae Praeparata, Radix Santophora, Radix Ginseng, Radix Angelicae Sinensis, Radix Scutellariae Sinensis, Radix Cicadae Sinensis, Dendrobium, Glycyrrhiza Uralensis. The above medicines are decocted in water, 1 dose daily, divided into two oral doses in the morning and evening, 10 days for a course of treatment, generally 1-3 courses of treatment, up to 5 courses of treatment. 3.1 Efficacy evaluation criteria: cured: facial pigmentation and other clinical symptoms disappeared; effective: facial pigmentation decreased and other clinical symptoms improved; ineffective: facial pigmentation did not decrease and other clinical symptoms did not improve. 3.2 Treatment results Among the 58 cases in this group, 27 cases (46%) were cured. 3.3 Typical medical history Patient Li, female, 30 years old, facial pigmentation sometimes more and sometimes less for 6 years, initially after 6 months of pregnancy, more than a year after delivery, improved on its own, half a year later because of depression, had taken vitamin C, vitamin E, prolotherapy pills, and so on. She had taken vitamin C, vitamin E and prolotherapy pills, but the effect was not obvious. In the past six months, facial hyperpigmentation has increased significantly, and the color has become darker, mostly on the cheeks under the eyes next to the nose. She is irritable and easily irritable, with occasional pain and distension, irregular menstrual flow, low volume and dark color with purple blood clots, dark red tongue with white fur and thin pulse. The evidence belongs to liver depression and qi stagnation. The veins are not smooth. He was given Formula No. 2 with the following addition and reduction: Chai Hu 12g, Fried Fragrant Herb 12g, Radix Angelicae Sinensis 15g, Chuanxiong 9g, Red Spoon 12g, Fried Peach Nut 9g, Safflower 9g, Gui Zhi 12g, Cicadelle 12g, Soapberry 9g, Licorice 3g, Colla Corii Asini (melted) 10g. 16 doses were taken on trial. At the follow-up examination, the facial pigmentation was significantly reduced and other conditions were good. 12 doses of the formula were taken and the patient was clinically cured. 4. The “Spiritual Pivot – Evil Qi Viscera Disease Form” says: “Twelve meridians, three hundred and sixty-five veins, their blood and qi are on the face and go to the empty (orifices)”, so facial color and internal organs have an intrinsic connection, and facial pigmentation, often due to pregnancy, fatigue, prolonged illness and other causes of the five viscera qi deficiency. The heart of the Hua in the face, the heart Qi is not enough to promote the normal movement of blood, blood color can not be glorified on the face; kidney essence deficiency, essence and blood is not full, kidney color floating outside, can lead to facial pigmentation. In addition, the lack of emotion and will can lead to liver depression and qi stagnation and stasis of the veins, which is manifested in the face as pigmentation, so the treatment of the disease must start with nourishing the heart, regulating the liver and nourishing the kidneys, “Su Wen – Four Diagnostic Fu Wei” said: “Qi is developed by the organs, the color follows the gas. The formula No. 3 is based on tonifying the kidney essence, which can transform qi and blood to nourish the face, and the color is blood energy, which is manifested on the surface of the skin. The combined use of all the herbs can enrich the essence and blood, harmonize the qi and blood, and make the face bright and moist.