Atherosclerotic stenosis and occlusion of the vertebrobasilar artery is an important pathogenesis of ischemic stroke in the posterior circulation. The general conservative medical drug treatment is mostly: improving circulation, dilation, antiplatelet aggregation, anticoagulation, fibrin-lowering and plaque stabilization therapy. Despite the use of aspirin or warfarin, stroke events in the area of the stenotic artery supply still occur in nearly 35.3% of patients. Stenting not only improves the blood supply to the distal part of the stenotic artery and relieves its clinical symptoms, but also prevents ischemic stroke due to atheromatous plaque dislodgement. According to the European SSYLVIA study, the annual risk of stroke in patients with vertebral artery stenosis treated conservatively with medical drugs alone can be 10%-24%, whereas the risk of stroke after endovascular stenting is 6.6% within 30 d and 7.3% within 1 year. Common complications of the procedure include subcutaneous hematoma at the puncture site, vertebral artery entrapment, rupture bleeding, thromboembolism due to plaque dislodgement, overperfusion syndrome, and postoperative restenosis. Endovascular stenting for stenosis at the opening of the vertebral artery is relatively safe and effective, with fewer complications.