There is a clear relationship between gastric ulcer and H. pylori, gastric ulcer accounts for about 80-90% of patients with H. pylori infection, for gastric ulcer with H. pylori infection, the treatment course is recommended for 8 weeks of time, positive for H. pylori, active anti-H. pylori treatment is recommended. In the case of gastric ulcer the recommended duration of anti-H. pylori is 2 weeks. Patients with gastric ulcer combined with H. pylori, the effect of this gastric ulcer treatment is generally better. If the ulcer is large and there is H. pylori infection, it is also necessary to rule out whether it is gastric cancer. If the biopsy is benign, the course of treatment must be followed by regular re-examination of gastroscopy and H. pylori.