On August 17, 2014, Professor Li Yigang’s team at Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, completed the first batch of left-ear occlusion surgery. 3 patients were successfully operated with left-ear occlusion in 3 hours. Atrial fibrillation is the most common persistent arrhythmia in clinical practice, with a prevalence of at least 1% in the general population. However, most patients with chronic atrial fibrillation have mild symptoms and are easily overlooked, but the potential risks are still high: firstly, it increases the overall mortality rate of patients; secondly, it leads to gradual enlargement of the heart and heart failure; thirdly, the complications of thromboembolism in chronic atrial fibrillation are significantly higher. Patients with non-valvular atrial fibrillation are five times more likely to have a cerebral infarction than the rest of the population. Chronic atrial fibrillation is on the one hand more dangerous and on the other hand more difficult to treat than paroxysmal atrial fibrillation. In the past, the percentage of patients with chronic atrial fibrillation who could maintain normal rhythm with either drug or electrotransfer therapy was low, and in the past decade or so, although catheter radiofrequency ablation of atrial fibrillation has become more and more mature with the advancement of radiofrequency ablation technology and experience, the cure rate of chronic atrial fibrillation is still lower than that of paroxysmal atrial fibrillation. The second patient we performed, Mr. Wang, who was a patient with chronic atrial fibrillation, had undergone RF ablation three times in 2012 at outside hospitals, using different strategies and procedures, including circumferential pulmonary vein isolation, linear ablation of the left atrium, and fracture potential ablation, but still could not maintain sinus rhythm even with the combination of drugs. For physicians, then, with a well-controlled ventricular rate, they have no choice but to recommend lifelong anticoagulation to reduce the risk of thromboembolism, but the structural and functional changes in the heart associated with long-term atrial fibrillation remain unavoidable. The choice of anticoagulant therapy is also very limited. The first is warfarin, the most used classical drug, which has been shown in many studies to reduce stroke by about 2/3. However, there are many problems with oral warfarin: its anticoagulant effect can cause bleeding complications while preventing thrombosis, its drug effect is affected by food and medication, and frequent hospital visits are required to monitor coagulation function during warfarin to prevent overdose. Thus, taking warfarin causes great inconvenience to patients. Especially in older patients, who are at high risk of bleeding and often cannot do regular hospital laboratory tests, warfarin therapy is poorly tolerated and adhered to in elderly patients. However, these patients are precisely the population at high risk of stroke. The second is dabigatranate, which has been rapidly rising in prescriptions abroad in recent years. Its biggest advantage over warfarin is that it does not require monitoring and is easy to apply, but the disadvantage is that it is too expensive, costing about $40-50 per day. So there are various practical problems with long-term use of anticoagulants, although it is true that they should be adhered to and are indeed effective. However, a careful analysis of this population shows that 87% of strokes are caused by thromboembolism, and 90% of the origin of this thrombus is gathered in the left heart ear. Therefore, in recent years, various blocking techniques for the left heart ear have become the latest technique for stroke prevention in patients with atrial fibrillation in Europe and the United States. Current follow-up data show that the occurrence of thrombus can be reduced by more than 90% after receiving this treatment. Therefore, for Mr. Wang, who has undergone RF ablation for 3 times, but is still in atrial fibrillation and has difficulty in transposition, blocking the left heart ear to reduce embolic events is a practical and effective means.