Since malignant tumors are a serious threat to human health and life, countries all over the world have invested a lot of human and material resources in cancer research. At present, the treatment of malignant tumors is not only the traditional three major treatment methods of surgery, chemistry and radiation in the past, but also includes the rapidly advancing biological treatment and various supportive treatment methods. Even though the traditional treatments such as surgery, chemistry and radiation are still used, the techniques and drugs used are not comparable to those in the past. Although impressive achievements have been made in the treatment of malignant tumors, they are still far from the requirements of people. With the improvement of people’s living standard, the incidence of esophageal cancer and gastric cancer has decreased, but the incidence of colorectal cancer has increased compared with the past. At present, surgery is still the main treatment method of GI tumors and one of the main means of palliative treatment. A part of early stage patients can be cured by surgery. However, because the current situation in China is to emphasize treatment rather than prevention, most of the tumor patients are already in the middle and late stage when they are found, so the possibility of getting a cure through surgery alone is greatly reduced. Therefore, the possibility of obtaining a cure through surgery alone is greatly reduced, and other treatments must be combined to obtain a high cure rate and a long survival period. Radiation therapy plays an indispensable role in the treatment of esophageal cancer, especially for patients who cannot be removed surgically. Radiation therapy is not very helpful for patients with gastric cancer that cannot be surgically resected, due to the difficulty of anatomical localization due to the constant peristalsis of the stomach and the resistance of gastric adenocarcinoma cells to radiation therapy. However, radiation therapy can relieve the symptoms of pancreatic cancer obstruction and alleviate chronic bleeding in unresectable lesions, and it can also treat patients with intraoperable gastric cancer. Radiation therapy also plays an important role in postoperative consolidation treatment of rectal cancer and patients with inoperable rectal cancer obstruction. Chemotherapy is commonly known as chemotherapy, which is usually used for preoperative, intraoperative and postoperative treatment of malignant tumors as well as palliative treatment of malignant tumors. Chemotherapy, as an important part of comprehensive tumor treatment, has made great progress in the treatment of digestive tract tumors. In addition to the traditional 5-fluorouracil, furanofurouracil, euflornithine, mitomycin C, adriamycin, cycloheximide, cis-chloroplatinum, etc., many new drugs such as siroda, oxaliplatin, paclitaxel, cisplatin and other chemotherapeutic drugs have been developed. The main chemotherapy methods are single-agent chemotherapy and combination chemotherapy, but it is generally believed that the effect of combination chemotherapy is better than single-agent chemotherapy. Preoperative chemotherapy can improve the efficacy of surgical treatment. Intraoperative chemotherapy is one of the important measures to prevent medical dissemination. Postoperative adjuvant chemotherapy is the most commonly used comprehensive treatment method for GI cancer. Postoperative chemotherapy mostly adopts combination chemotherapy, and there are many kinds of combination chemotherapy regimens, but generally 5-Fu and DDP are the basic drugs. Postoperative adjuvant chemotherapy can prevent postoperative recurrence of tumor patients. Chemotherapy has an important palliative role for postoperative recurrence patients. Intraperitoneal chemotherapy has a special status in the treatment of gastrointestinal tract tumors, especially for tumor patients with abdominal lymph node metastasis and plasma membrane invasion. Prospective studies have shown that intraperitoneal chemotherapy can reduce intraperitoneal recurrence and liver metastasis. With the progress of science and technology, biologic therapy has gradually escaped from the perception of being a theoretical giant and a clinical dwarf, which was recognized in the past, and become a truly effective treatment. This has been confirmed in the treatment of lymphoma and breast cancer. In the gastrointestinal tract tumors more research is colorectal cancer, the main treatment tools are: 1. monoclonal antibodies: such as anti-vascular endothelial growth factor monoclonal bevacizumab (Bevacizumab, Avastin); such as anti-epidermal growth factor receptor monoclonal cetuximab (Cetuximab, C-225, Erbitin). Patients with her-2 overexpression in gastric cancer can also be treated with Herceptin. 2.Tumor vaccine: such as tumor cell vaccine, peptide vaccine, virus vaccine, protein vaccine, dendritic cell vaccine, etc. In particular, monoclonal antibodies combined with chemotherapy and other means have achieved better efficacy. Among the molecularly targeted therapeutic agents, Gleevec has a notable performance in the treatment of gastrointestinal mesenchymal tumors. Various supportive therapies have a positive effect on prolonging the survival of tumor patients. Among them, various stents play an important role in relieving the obstruction of esophagus and gastrointestinal tract; parenteral nutrition is very important for advanced tumor patients; various antiemetic drugs and leukocyte-raising drugs have an inestimable role in completing radiotherapy and chemotherapy for tumor patients. Chinese herbal medicine has been used to treat malignant tumors in China for thousands of years. Combining with TCM treatment can reduce toxic side effects, strengthen anti-cancer effects, enhance immune function, prevent recurrence and metastasis, and improve survival quality and survival rate. Chinese herbal medicine can also be used as a follow-up treatment after the completion of western medical treatment.