Although plasma therapy for recovered patients is effective in severe and critically ill patients, it may also induce “inflammatory storms”. Moreover, as a blood product, transfusion of this exogenous substance into the body may lead to allergic reactions and imported infectious diseases. Most patients with Neoplastic pneumonia who recover from treatment will develop specific antibodies against the Neoplastic virus, which can kill and clear the virus. Plasma containing high-valent neocoronavirus-specific antibodies donated by recovered patients is treated with virus inactivation and used mainly for the treatment of critically ill patients with neocoronavirus. In the absence of a vaccine and specific therapeutic drugs, treatment with plasma from recovered patients can significantly reduce the death rate of critically ill patients. In critically ill patients, salvage therapy is a necessary option and the risks are much less than the benefits.