Five Heart Troublesome Fever refers to heat in the two hands and two feet, and the self-consciousness of the heart and chest. For different causes, there are different drugs for the treatment of different evidence, as follows: 1. Yin deficiency: causing Five Heart Troublesome Fever, the formula is added and reduced with the evidence with Clear Bone San, commonly used herbs are Yin Chai Hu, Hu Huang Lian, Gentiana Macrophylla, Turtle Nail, Ground Bone Peel, Artemisia, Zhi Mu, etc. If the kidney yin deficiency is the main cause of the five heart troubles, you can choose Liu Wei Di Huang Wan; if the five heart troubles are accompanied by yin deficiency and night sweating, you can choose Angelica Sinensis Six Huang Tang; if the five heart troubles are accompanied by soreness in the waist and knees, Zhi Bai Di Huang Wan; if the five heart troubles are accompanied by bone steaming and hot flashes, use Da Yin Wan; 2. Commonly used herbs are Artemisia annua, turtle nail, Zhi Mu, Sheng Di, etc.; 4. Fire-heat internal stagnation: leading to five heart troubles and heat, the formula uses Fire Yu Tang with addition and subtraction, commonly used herbs are Sheng Ma, Ge Gen, Chai Hu, Paeonia lactiflora, Fang Feng, Licorice, etc.; although five heart troubles and heat are yin deficiency, they are always heat evidence, which should be treated with evidence. In addition, the diet needs to identify dietary evidence, can be appropriate to eat cold food, for beef, mutton, cinnamon, red dates and other hot food to eat less, so as not to aggravate the symptoms.