Hepatitis B virus is a DNA virus belonging to the hepatophilic DNA virus family, which uses RNA intermediates as templates for the synthesis of DNA strands by reverse transcription. Three forms of particles are present in the serum of HBV-infected patients when observed under electron microscopy: Dane particles, small spherical particles, and filamentous or nucleated particles. In general, serum has the most small spherical particles and the least Dane particles. I. Common detection methods In China, 50% to 70% of people have been infected, and due to the widespread use of hepatitis B virus vaccine, the hepatitis B surface antigen carriage rate is about 7.18% of the total population, which is a moderately endemic country. Currently there are mainly immunological methods and molecular biological diagnostic methods for hepatitis B virus infection. Among the immunological methods commonly used clinically are enzyme-linked immunosorbent assay (ELISA), solid-phase radioimmunoassay, colloidal gold immunochromatography, time-resolved immunofluorescence, microparticle enzyme immunoassay, chemiluminescence and electrochemiluminescence assay (ECLIA), etc. Second, before the test patients need to pay attention to 1, before doing hepatitis B two to half should be careful not to drink alcohol. 2, if you are still taking certain drugs before the test, then it is best to stop using the drugs a day or two before the test to avoid affecting the test. 3, before doing the hepatitis B and half test, also pay attention to ensure adequate rest, because poor sleep, fatigue, etc. may affect the accuracy of the test results. 4, in the night before the test it is best not to eat greasy, spicy food. 5, hepatitis B two to half before the test is not required fasting, but if you also need to check liver function, blood lipids and other items, it is a different story. The hepatitis B virus seriously affects people’s health, and how to properly manage this situation is something that our nationals should pay attention to. In fact, to answer this question exactly, we also need to analyze, that is, what is a major triplet, specifically HBsAg, HBeAg and HBcAb three positive, indicating that the body is infected with hepatitis B virus, hepatitis B virus in the body has a significant replication capacity, whether the need to treat the major triplet, but also combined with the specific circumstances of the patient (age, family history), liver function, color ultrasound and HBVDNA and other indicators examined at that time together, in order to answer this question, if the patient is relatively young (less than 30 years old), no family history of cirrhosis, liver cancer, only the major triplet, HBVDNA positive, normal liver function, color ultrasound is also not seen abnormal test results, such a situation belongs to hepatitis B virus carriers, that is, infected with This situation is not recommended for treatment, but attention should be paid to regular re-examination. Because the onset of chronic hepatitis B is not the hepatitis B virus direct damage to liver cells, but the hepatitis B virus and the body’s immune system interaction, the damage to liver cells in the liver, so all cases of hepatitis B virus infection, must be regularly re-examined to grasp their liver function changes, once the liver function is obviously abnormal, we must do targeted differential diagnosis to see if the cause of the hepatitis B virus If you can’t tell whether it’s caused by the hepatitis B virus, you can consider liver pathological examination if necessary, that is, liver biopsy, through the results of liver pathological examination, to clarify the cause of liver function abnormalities and the degree of lesions, if it is determined that the patient meets the indications for antiviral treatment, we should consider antihepatitis B virus treatment, so what antiviral treatment drugs are used for treatment? The actual antiviral treatment for hepatitis B is currently available in two categories 1, interferon and oral anti-hepatitis B virus drugs. 2, interferon including ordinary interferon and long-acting interferon two categories; oral anti-hepatitis B virus drugs include: lamivudine, adefovir, telbivudine, entecavir and tenofovir five kinds of oral drugs. The goal of treatment is to maximize the long-term inhibition of hepatitis B virus replication, that is, to inhibit HBVDNA replication, reduce the inflammatory necrosis of liver cells and liver fibrosis, to delay and reduce liver failure, cirrhosis decompensation, primary hepatocellular carcinoma and other complications, so as to improve the quality of life and prolong survival time, as to which anti-hepatitis B virus treatment option to choose, it is recommended to ask As for which anti-hepatitis B virus treatment option to choose, it is recommended to ask the help of a specialist to choose a more suitable treatment option for you.