Leukemia accounts for one-third of the total incidence of childhood tumors and is the most common malignancy in children. How can parents detect the signs of leukemia in their children in time? What treatment options are available for childhood leukemia? Can childhood leukemia be cured? How to prevent leukemia in daily life? Symptoms: Three Danger Signs of Childhood Leukemia Most acute leukemias in children have an acute onset and are characterized by fever, anemia and bleeding in the early stages. Due to the proliferation of leukemia cells in the bone marrow and the production of substances that inhibit normal hematopoiesis by leukemia cells, normal hematopoiesis is inhibited and peripheral blood granulocytopenia, anemia and thrombocytopenia occur. Granulocytopenia predisposes to infection, and thrombocytopenia leads to bleeding. 1.Fever This is the most common first symptom. One of the causes of fever is tumor fever, that is, leukemia cells themselves release thermogenic substances, causing an increase in body temperature; another cause is secondary infection, due to the lack of normal white blood cells, especially mature granulocytes, the normal defense function of the body is impaired, thus causing infection and fever. Therefore, when a child has a fever of unknown origin (especially repeatedly), parents should be more vigilant and should not think that their child has a simple cold and fever, but must send them to the doctor in time. 2. Anemia The most common early symptom. Leukemia cells cause inhibition of hematopoiesis in the red blood cell lineage, resulting in a decrease in red blood cells and hemoglobin, which leads to varying degrees of anemia. In the early stages of anemia, the symptoms often include pallor, dizziness, low appetite, shortness of breath, ringing in the ears, and swelling of the face, and these signs can become more and more severe. If a child who is usually active appears to be inactive and prefers to be still, pay attention to the presence of anemia. Bleeding More than half of the children with leukemia have varying degrees of bleeding. The most common sites of bleeding are the skin and mucous membranes, often manifested as bleeding spots or bruises on the skin, nosebleeds, bleeding gums, blood bubbles on the tongue of the mouth, etc. Girls with menstruation will experience increased menstruation. In severe cases, internal organs and intracranial bleeding may occur, such as vomiting blood, coughing up bloody sputum, resolving black stools, and hematuria, which can lead to death in children. In addition, childhood leukemia may cause enlargement of the liver, spleen, and lymph nodes. Leukemia cells may infiltrate the central nervous system, leading to headaches, nausea, vomiting, and even convulsions and coma in affected children. Prevention: Expose children less to chemical toxins Compared to adult leukemia, childhood leukemia has a higher cure rate, especially for acute lymphoblastic leukemia, and most children under the age of 9 do not need a bone marrow transplant and may be cured by drug chemotherapy. The current treatment for childhood leukemia is mainly combined chemotherapy, and most children can recover through the regular chemotherapy process, with a few high-risk children requiring bone marrow transplantation. The treatment period for childhood leukemia is longer than that for adults, usually 2-3 years, and parents should have sufficient patience and psychological preparation to fight the disease with their children for a long time. If, after 2-3 years of chemotherapy, the drug is stopped and observed for 5 years without relapse, relapse is less likely after that. The academic consideration is 5 years of disease-free survival, but there is a socially considered cure for leukemia. Studies have shown that exposure to some chemicals does increase the risk of leukemia in children, and parents should try to avoid exposing their children to chemical toxins, such as decorating with environmentally friendly materials as much as possible, and ventilating newly renovated houses for several months to six months before moving in is more appropriate. Open the windows and ventilate before moving in, and if possible ask the indoor environment monitoring department to carry out tests, and then move in after passing, paying particular attention to avoid benzene pollution. In case of unexplained bleeding, fever, joint pain, dizziness and other symptoms, it is best to go to the hospital for examination. In addition, avoid direct contact with chemicals. Of course, the prevention of acute leukemia in adults is the same as in children, avoiding contact with chemicals as much as possible, including hair dyes of unreliable quality.