In the anorectal department, occasionally a patient will ask a similar question to regulate the atmosphere, often causing the doctor to smile, but the patient who asked the question is a face of confusion, he or she will say: “Doctor, I heard from my family that there are male and female hemorrhoids, male hemorrhoids can be cured after surgery, female hemorrhoids will still be born after surgery, so is my hemorrhoid a male or a female? I’m not sure if my hemorrhoids are male or female, but will they still recur after surgery?” There was also a time when patients were lined up at the door to change their medication, and I heard a female patient say, “I don’t know what kind of hemorrhoids I have, what are mixed hemorrhoids? A male patient seriously replied, you are a female hemorrhoid, I am a male hemorrhoid, we both add up to a mixed hemorrhoid. There was a burst of laughter inside and outside the door. It is true that the concept of hemorrhoids has a mother hemorrhoid area, the so-called mother hemorrhoid area, is the anal canal rectal mucosa range at the truncated position 3, 7, 11 points at the anus. The etiology of hemorrhoids is broadly outlined in two theories, one of varicose veins and the other of inferior displacement of the anal cushion. In the varicose vein theory, the cause of hemorrhoids is mainly due to obstruction of venous reflux, venous stasis, and dilatation. The submigration theory argues that the formation of hemorrhoids is a mass formed by pathological hypertrophy and displacement of the anal cushion and stagnation of blood flow in the perianal subcutaneous vascular plexus. There are three arteries supplying rectal blood: the middle sacral artery, the superior rectal artery, and the inferior rectal artery, all of which are derived from the abdominal aorta, the largest vessel in the abdominal cavity. Among these three branches, the main one is the superior rectal artery, which runs through the whole rectum from top to bottom and forms three densely distributed areas in the left middle, right anterior and right posterior of the lower rectum (3, 7 and 11 o’clock in the truncated position). If there is a problem with venous reflux, the local rectal venous plexus becomes stagnant and overly dilated, forming internal hemorrhoids. Most of the internal hemorrhoids we see clinically are distributed in these three areas, so these three areas are also called the mother hemorrhoid area. Two vascular networks are distributed near the anorectum, the rectal plexus at the lower end of the rectum and the anal plexus at the edge of the anus, and they become hemorrhoids. The rectal venous plexus is overextended to form internal hemorrhoids and the anal venous plexus is overextended to form external hemorrhoids. The junction of the anal canal and rectum is an annular structure called the dentate line. Internal hemorrhoids occur above the dentate line and are covered with rectal mucosa and bleed easily. The hemorrhoids that occur below the dentate line are called external hemorrhoids. The surface is covered with the mucosa of the anal canal. The hemorrhoids formed by the venous plexus above and below the dentate line are called mixed hemorrhoids. The internal hemorrhoids are mainly bleeding in the early stage, but the bleeding will be reduced in the later stage due to local fibrosis, but it will cause severe internal hemorrhoids to prolapse and external hemorrhoids to edema that is mixed hemorrhoids to become embedded, which will cause severe swelling and pain and produce a lot of mucus, and the patient is often in pain. So is it possible to eradicate hemorrhoids after surgical removal of hemorrhoids in the mother hemorrhoid area? Hemorrhoids cannot be eradicated, nor are they recurrent and are best defined as regenerative. Post-operative hemorrhoid regeneration boils down to two factors, one is the patient himself, due to careless lifestyle habits and local anatomy, and the other is from the operator, whether the surgery deals with most of the hemorrhoids at once and protects the anal canal skin mucosa well, whether it deals with the loose rectal mucosa that is highly correlated with prolapsed hemorrhoids, and whether it pays attention to the impact of anorectal pressure on hemorrhoid regeneration in the subsequent recovery. Treatment of hemorrhoids needs to follow the principle of individualization, starting with a comprehensive assessment of the condition based on the patient’s symptoms and signs, followed by an appropriate treatment approach that has both commonalities and individuality. It is still misleading to make the treatment too simple.