What is thermal perfusion? When we talk about thermal perfusion, we need to know about thermal therapy first. The so-called thermal therapy refers to a type of treatment method that uses heat to treat tumors. Cells have different sensitivity to temperature and different tolerance to temperature, just like some people are afraid of heat and some are not. Compared with normal tissue cells in human body, tumor cells have high sensitivity to temperature and are more afraid of heat. Therefore, as long as the tumor tissue is heated to a level that exceeds its heat tolerance, the proliferation of tumor cells can be curbed and they will slowly apoptosis. Usually, this temperature is controlled at about 43℃, which exceeds the heat resistance of tumor cells but is within the heat resistance of normal cells, and is a safe and effective tumor treatment method. Thermal perfusion is a new tumor treatment modality based on thermal therapy and incorporating chemotherapy technology. In this way, a catheter is implanted into the body by puncture or minimally invasive surgery, and the tumor cell-killing treatment fluid is automatically heated in the treatment machine, then heated through the catheter into the body cavity, and then heated again through another catheter back into the treatment machine, establishing an extracorporeal circulation system to kill tumor cells continuously and effectively at a constant temperature. Before the advent of thermal perfusion, traditional body cavity perfusion was performed by surgically implanting a catheter, heating saline and then injecting it into the body through the catheter, but the operation was complicated and easily caused heat loss. If there is water accumulation in the patient’s body, the temperature of the injected saline will not reach the temperature needed for treatment if it is neutralized again, which will greatly affect the therapeutic effect, while thermal perfusion can keep the injected liquid at a constant temperature of 45 degrees through an extracorporeal power heater, which will not affect the therapeutic effect due to temperature drop. Many patients know that the side effects of chemotherapy are great. Although thermal perfusion is a new technology, it is still necessary to use chemotherapy drugs after all, so are the side effects as great as chemotherapy? Director Wu explained, “Thermal perfusion can improve the efficacy of chemotherapy drugs, we can use a smaller amount of drugs directly in the body cavity to achieve the same therapeutic effect, so compared with conventional chemotherapy, the side effects of thermal perfusion are much smaller.” In addition, for tumor patients with fluid accumulation in the body, surgical aspiration is sometimes not clean, and the remaining fluid is likely to lead to adhesions, encapsulation or even intestinal obstruction in the body cavity, while thermal perfusion can avoid these sequelae while treating the lesion and effectively curbing the regeneration of fluid from the root. Which patients are suitable for thermal perfusion? Thermal perfusion makes the advantages of heat therapy and chemotherapy complementary, which can improve the efficacy of chemotherapy while killing tumor cells, improve the immunity of the body, curb the proliferation and metastasis of tumor cells, eliminate the lesions that cause cancerous effusion, and achieve the purpose of effective treatment of cancerous effusion, which is mainly applicable to the intraoperative and postoperative treatment of gastric cancer,,, esophageal cancer, intestinal cancer, pancreatic cancer, ovarian cancer, uterine cancer, pleural effusion caused by malignant tumor, peritoneal effusion, pericardial effusion and septic peritonitis caused by malignant tumors, as well as the prevention and treatment of tumor cell spreading and metastasis, and it is also very effective in eliminating pain symptoms in some advanced stages of tumors.