Since the etiology of SLE is unknown, there is no specific drug yet, and the specific performance of each patient is different, so the treatment should be individualized. The following are several drugs commonly used in the treatment of SLE: 1. Non-steroidal anti-inflammatory drugs: common diclofenac, celecoxib, ibuprofen, fenbuterol, anti-inflammatory pain, fotarol, etc. are all such drugs, which are used for symptomatic treatment of symptoms such as fever, joint swelling and pain, and muscle pain. 2. Glucocorticoids: This drug is still the main drug for the treatment of SLE. Currently, the commonly used drugs are: prednisone (5mg/tablet) and methylprednisolone (4mg/tablet). Hormonal drugs are suitable for acute active cases, especially acute eruptive lupus, acute lupus nephritis, acute central nervous system lupus and combined severe anemia, leukopenia and thrombocytopenia. However, it must be emphasized that the dosage must be reduced as much as possible under the control of disease activity, but the drug should not be stopped abruptly to avoid aggravation of the disease. 3.Anti-malarial drugs: mainly chloroquine and hydroxychloroquine, which are very effective in controlling skin damage (pteroidal erythema, discoid erythema), photo-allergy and arthritis, but the effect is slow and requires a longer period of time to be effective. 4.Immunosuppressants: For patients whose condition cannot be controlled by glucocorticoids alone, and patients with more serious renal damage and neurological damage should consider applying immunosuppressants. The most commonly used is cyclophosphamide, whose side effects include bone marrow suppression, reduced immune function, gonadal suppression, etc., so pay attention to the review of liver function and blood routine when using the drug. Other optional immunosuppressants are azathioprine, methotrexate, etc. 5, Chinese medicine treatment: the combination of Chinese and Western medicine treatment is conducive to improving the efficacy, the clinical application of more traditional Chinese medicine are Lei Gong Tang, should be used under the guidance of doctors. During the period of taking Chinese medicine, hormones should not be stopped without authorization to avoid aggravating the disease.