The patient, female, 60 years old, complained of pain in the right lower abdomen for 20 years with burning sensation and radiating to the upper medial thigh, with no radiating pain below the knee joint. The pain VAS score was 7-8, and examination of the site where the iliac inguinal nerve crosses the transversus abdominis muscle led to positive Tinel evidence. A 7-cm-long post-operative incision scar for hernia was also seen at the level of the anterior superior iliac spine in the right lower abdomen. Ultrasound of the abdomen and pelvis was unremarkable, and colonoscopy was unremarkable. The patient sought medical attention from multiple sources and was treated for gynecological and gastrointestinal diseases. The iliac inguinal nerve injury was considered, followed by iliac inguinal nerve block with 0.5% ropivacaine 6ml and methylprednisolone 40mg, and the pain disappeared after the block, which was maintained for 24h, and the pain returned. Later, the nerve was considered to be damaged by herniation surgery and radiofrequency treatment was considered to be given. The patient complained that the pain disappeared, and was given 1% lidocaine 2ml and methylprednisolone 40mg paraneoplastic injection. Celecoxib was also given orally for 7 days. The pain disappeared on the second postoperative day, and the VAS score was 1-2 on the fifth day of follow-up. This is the first patient in our department who underwent ultrasound-guided nerve radiofrequency treatment. The successful diagnosis and treatment of this patient marked a new stage of pain treatment in our department. Most of the patients who were misdiagnosed or missed in many hospitals were finally diagnosed and treated by our department, and the patients returned with satisfaction.