Today we introduce some knowledge of radiation therapy for benign diseases. As a supplement to the treatment of other sister departments in the clinic, the role of radiation therapy is certain, and many diseases in the specialist treatment repeatedly exhausted all means and symptoms persist, try to do radiation therapy will have unexpected effects. Of course! There is a principle that needs to be clear first, radiation therapy is not encouraged as the first choice of treatment for benign diseases! 1: Take a cautious attitude, never abuse, and minimize the risk factors because 1): normal tissues have a certain amount of tolerance to radiation 2): there is a certain impact on genetics 3): children’s problems 4): radiation carcinogenesis 2: weigh the pros and cons, consider the benefits and risk factors, reasonable trade-offs, and immediate treatment 3: other specialist treatments are difficult to be effective Caution 1: First of all, make a clear diagnosis. The patient suffers from the disease either because of pain, strange itching or affecting the appearance, or because it affects the function, there is a need for treatment, and the patient has a strong demand for treatment. 2: Detailed knowledge of the disease and medical history, knowledge of the history of previous treatment, especially whether there is previous radiation therapy. 3: According to the knowledge and experience of the literature, radiation therapy has a relatively obvious and certain efficacy for the disease suffered. 4: The disease suffered has failed after various other non-radiation treatments. 5: Let the patient understand the effectiveness of radiation therapy, the advantages and disadvantages of radiation therapy compared with other treatment methods, and the possible side effects and dangers of radiation therapy. 6: The dose of irradiation should be low rather than high. 7: The adjacent normal tissues should be avoided and protected to the maximum extent possible during treatment. Some benign diseases applicable Various benign skin diseases: keloid tumor, hemangioma, keratoacanthoma, common and plantar warts, condyloma acuminata, corns and calluses, ringworm, beard sores, abscess penetrating perifolliculitis of the head, neurodermatitis, eczema, vulvar and perianal skin scratching, psoriasis, sweat gland itch (Fox-Fordyce disease), seborrheic dermatitis, acanthosis, (hyperhidrosis, odoriferous sweating, (hyperhidrosis, odorous sweating, pigmented sweating), axillary sweat glanditis, suppurative sweat glanditis, lymphatic fistula, herpes zoster, boils and carbuncles, dermatitis, nail fungus, hirsutism, granuloma annulare, lichen planus. Benign ocular and orbital diseases: Graves’ ophthalmopathy, age-related macular degeneration, intraorbital inflammatory pseudotumor, pterygium. Benign diseases of the ear, nose and throat: nasal sclerosis, involute papilloma, secretory otitis media, nasopharyngeal angiofibroma, chronic tonsillitis, adenoid hypertrophy and inflammatory lymphoid hyperplasia, jugular venous bullae, isolated extramedullary plasmacytoma. Benign oral diseases: oral leukoplakia, enameloblastoma, parotid fistula, parotitis, Mikulic disease. Benign diseases of the digestive system: hepatic hemangioma (including some newborns and children), pancreatic fistula, biliary fistula, lymphatic fistula, esophageal hemangioma. Benign diseases of the genitourinary and endocrine system: sclerosing penile corpus cavernosum, benign prostatic hyperplasia, ovarian denervation (rarely done nowadays), male breast enlargement. Benign diseases of bone and joint: pigmented villous nodular synovitis, giant cell tumor of bone, hemangioma of bone, aneurysmal bone cyst, Gorham’s disease, osteoblastoma, ectopic ossification, painful degenerative osteoarthrosis, chronic osteomyelitis. Benign hematologic disorders: idiopathic thrombocytopenic purple epilepsy (ITP) thrombocytopenic purple epilepsy due to giant cavernous sinusoidal hemangioma. Benign soft tissue diseases: fibromatosis, Langerhans’ histiocytic histiocytosis, eosinophilic lymphogranuloma, cervical lymphadenitis, thrombophlebitis, palmar tendon contracture. Benign diseases of the central nervous system: pituitary adenoma, cranial inflammatory duct tumor, suprasellar area occupying disease, meningioma, chordoma, choroid plexus papilloma, spinal cavernous disease. Benign diseases of the immune system: autoimmune diseases: multiple sclerosis, lupus nephropathy, rheumatoid arthritis, myasthenia gravis. Organ transplantation: organs and bone marrow. This article only lists some benign diseases that are currently carried out and that I have done, without detailed explanation, and specific needs can be consulted and explained individually.