After a pimple becomes hardened, it can usually go away with professional treatment. Acne, also called acne, manifests itself in a variety of ways. It may be acne similar in color to the skin, it may be occlusive whiteheads, it may be blackheads, or it may be inflammatory papules, pustules, nodules, cysts, scars, etc. Red inflammatory acne may slowly form nodules, cysts or scars as the condition worsens, at which point hard lumps will form, mainly as a sign of severe acne, which requires aggressive treatment at a hospital dermatology department. For such patients, oral doxycycline and isotretinoin soft capsules can be taken, along with the use of adapalene gel at night; hot compresses can also be applied every night and mucopolysaccharide polysulfate cream can be applied to promote remission; if severe nodules or keloids are not treated with medication, surgical removal can be considered. During treatment, patients need to be careful not to squeeze the acne with their hands to avoid spreading the inflammation and forming nodular acne marks, which will affect the aesthetics.