At present, the common clinical treatment of proctitis drugs are anti-infective drugs, antipyretic and analgesic drugs, salicylic acid drugs, glucocorticoids, immunomodulators, etc., and the specific medication varies from person to person. 1. Anti-infective drugs: antibiotics: such as doxycycline, cefuroxime, etc., for bacterial infections; antiviral drugs: such as acyclovir, vasiclovir, etc., for viral infections. 2. Antipyretic and analgesic drugs: such as mesalazine, mainly used for ulcerative proctitis and radiation proctitis. 3. Salicylic acid drugs: mainly including salicylazosulfapyridines, salicylic acid drugs for the treatment of proctitis is very good, however, this drug decomposition of sulfapyridine has a certain damage to the liver, the use of drugs must pay more attention. 4. Glucocorticosteroids: Glucocorticosteroids are a kind of drugs used in the treatment of proctitis, such as prednisolone. The side effects are large, and it is not suitable for patients to take for a long time. 5. Immunomodulators: mainly including azathioprine, cyclosporine toxin, etc., mainly through the inhibition of the body’s immune system to further control the development of inflammation, thus leading to the therapeutic effect. In summary, proctitis due to the cause of the disease, clinical manifestations of different therapeutic drugs will be different, and more types of drugs available, therefore, the diagnosis of proctitis must be under the guidance of the doctor for the choice of drugs, do not blindly use drugs or increase or decrease the dosage of their own, so as not to cause adverse consequences.