Large solid enameloblastoma often destroys the bone cortex of the jaws and easily invades the surrounding normal tissues, which is not easy to remove cleanly and has a high recurrence rate after surgery. My personal experience is to first perform decompression surgery to reduce the cystic cavity of enameloblastoma and confine the tumor to the jawbone. At this point, radical surgery is then performed to remove the tumor involved jawbone, and then functional reconstruction of the jawbone defect (such as using fibula or iliac flap), which has a low recurrence rate after surgery. Yesterday’s surgical patient was a patient with enameloblastoma of the mandible, and after I treated him with this method, the lesion was confined to the mandible, creating the conditions for another complete surgery.