The clinical manifestations of mesenteric lymph node enlargement in children include nausea, vomiting, abdominal pain and other symptoms, mainly paroxysmal pain around the umbilicus. If the diagnosis is clear and the child has no history of drug allergy, he can take oral amoxicillin clavulanate potassium anti-infection treatment. During the period of illness, attention should be paid to eating light, easily digestible food. It is also important to take better care of the child to avoid recurrence and aggravation of the disease due to cold or improper food intake. Because lymph nodes are normal human tissues, inflamed lymph nodes will shrink slightly after treatment, but usually will not drop to normal.