In order to lower glutathione, the cause of its elevation should be addressed and the appropriate methods of lowering it should be taken. Because glutathione is mainly present in liver cells, the elevation of glutathione is mainly due to damage to liver cells, in addition, glutathione can also appear when the biliary tract is obstructed. In addition, there are also factors outside the liver and gallbladder, such as poor work habits, some drugs, toxins and other factors, which can also cause an increase in ALT. To reduce these causes of ALT elevation, you need to use the following different methods: 1, work and rest reasons: often stay up late to cause the elevation of ALT, should adjust the work and rest time, to develop good work and rest habits, after not staying up late, ALT can gradually drop back to normal values; 2, liver and gallbladder disease causes: liver disease causes the elevation of ALT, such as viral hepatitis, alcoholic liver, fatty liver, etc., you need to target the original cause of ALT. The clinical use of entecavir can inhibit the replication of hepatitis B virus and repair the liver, thus reducing transaminases. Alcoholic liver patients need to stop drinking, fatty liver patients need to actively exercise, weight control; biliary obstruction may also require surgery to unblock the bile ducts in order to reduce the ghrelin; 3, drugs and toxins: such as chlorpromazine, isoniazid, carbon tetrachloride, organic pesticides, etc. can also lead to elevated serum ghrelin, at this time, the patient should be immediately sent to the hospital, as soon as possible, enema, to reduce the toxic effects of toxins, and Use the corresponding antidote for detoxification; 4. Other causes: such as malnutrition, alcoholism, cardiomyopathy, cerebrovascular disease, skeletal myopathy, pancreatitis, etc., need to treat the original disease first, and generally when the original disease is cured, the glutathione transaminase will drop back to normal values.