Duodenal ulcer will not become cancerous, only a few gastric ulcers may become cancerous, so there is no such thing as duodenal ulcer cancer. For the clinical symptoms of duodenal ulcer, it is mainly regular pain in the upper abdomen, and the location of abdominal pain is mostly located under the glabella or left upper abdomen. The abdominal pain is characterized by distension, and it is mostly paroxysmal, usually more obvious when hungry and in the early hours of the night. The pain may be relieved after eating, or after taking acid-suppressing drugs, and may be accompanied by nausea, vomiting, acid reflux, belching, and loss of appetite. If the ulcer is complicated, clinical symptoms may also occur, such as black stool if the ulcer is bleeding or frequent vomiting if the ulcer is obstructed. If the ulcer is complicated by perforation, peritoneal irritation may occur. Patients who clearly have a duodenal ulcer need to cooperate with the specialist in the regular use of medication to avoid serious complications of the ulcer.