(Disclaimer: This article is only for scientific purposes, in order to protect the patient’s privacy, the relevant information in the following content has been processed) Abstract: The patient, Ms. Zhang, had erythema and papules on her nose half a year ago, which were not treated, and then the symptoms became more and more serious, so she came to our hospital and was diagnosed with rosacea. After active medication with physical therapy, the patient’s symptoms were controlled. However, because the patient did not follow the doctor’s instructions for review, rosacea recurred again, again with medication and regular follow-up, rosacea was cured and did not recur. Basic information] Female, 45 years old [Disease type] rosacea [Consultation hospital] Maanshan Seventeen Metropolitan Hospital [Consultation time] February 2022 [Treatment plan] medication (doxycycline hydrochloride tablets + fusidic acid cream + isotretinoin soft capsule) + LED red light irradiation treatment [Treatment cycle] outpatient treatment for 15 weeks [Treatment effect] rosacea cured A. Initial consultation Ms. Zhang got some small red bumps on her nose six months ago. Half a year ago, Ms. Zhang’s nose developed some small red packets, which caused her nose to be flushed, but it didn’t hurt or itch, so she didn’t pay too much attention to it. Later, the symptoms of nose flushing became more and more serious and difficult to subside, especially after eating spicy food or beef or mutton, the symptoms of nose flushing would be more obvious, and at the same time, sun exposure would also aggravate the symptoms of nose flushing. One day ago, the patient drank some wine at a friend’s party, and on the second day, he found that the redness of his nose had worsened significantly, and small red bumps appeared around his nose, so he came to the hospital for treatment. After carefully checking the patient’s face, he found dark red spots on the nose and nasolabial folds, surrounded by red inflammatory papules, and was diagnosed with rosacea. After treatment, rosacea belongs to a kind of skin immunity inflammation problem, mostly related to skin immunity disorder and mite infection, which is easy to recur. Since the patient has obvious inflammatory reaction in the nose and nasolabial folds, doxycycline hydrochloride tablets were given orally, and fusidic acid cream was given externally for anti-inflammatory and mite-killing treatments, and LED red light irradiation was also given for anti-inflammatory treatment, and the patient was also asked to come to the clinic for follow-ups on a regular basis. After 2 weeks of treatment, the redness of the nose and nearby areas was significantly reduced, so the patient felt that he had been cured and did not come for follow-up. However, one week later, after sunbathing, redness and pimples started to appear on the nose again, so the patient came back to the clinic again. Considering that the patient was suffering from a recurrence of rosacea, he was given isotretinoin soft capsules to take orally, with monthly follow-ups during the medication period to prevent recurrence. This time, the patient strictly followed the requirements of the medication, and every month regular follow-up, after 12 weeks, the patient came back for follow-up, the face did not appear flushing, pimples and other symptoms, to achieve a more satisfactory therapeutic effect, and was allowed to stop the drug, the treatment cycle of a total of 15 weeks. Fourth, the precautions I am glad that the patient after a series of active treatment, rosacea has achieved satisfactory results. As rosacea often recurs, patients still need to pay attention to the following situations in their daily life: 1, patients need to pay attention to adjusting their own emotions in their daily life, avoiding excessive pressure and anxiety, and at the same time pay attention to resting on time, going to bed early and getting up early, and developing good living habits; 2, they should try to avoid spicy and stimulating foods such as chili peppers, beef, mutton and other foods, and avoiding smoking and drinking alcohol; 3, patients should try to avoid spicy and stimulating foods such as chili peppers, beef, mutton and other foods, and avoiding smoking and drinking alcohol when they are out of bed, Patients should pay attention to facial sun protection when going out and avoid direct sunlight as much as possible; 4. Since rosacea is often combined with skin sensitivity, patients should pay attention to the application of mild, non-stimulating, fragrance-free and preservative-free skincare products when using skincare products in their daily life. V. Personal perception The occurrence of rosacea is often associated with skin immune disorders, mite infections, in addition, sun exposure, staying up late, as well as eating stimulating foods, alcohol and other factors are also prone to lead to the onset of the disease. Treatment requires individualized medication based on the patient’s inflammatory state. As rosacea is prone to recurrence, its treatment cycle usually takes several months, so patients need to have a certain degree of patience. In this case, the patient did not follow the doctor’s instructions and stopped taking the medication because he thought he had been cured, which led to a relapse of the disease. This shows that it is equally important to strictly follow the doctor’s instructions when taking medication to control the disease.