(Disclaimer: This article is only for popularization purposes, in order to protect the privacy of the patient, the relevant information in the following content has been processed) Abstract: Although stretch marks do not hurt, but a white stripe on the abdomen does affect the aesthetic appearance. In this article, the patient came to our clinic because she had a lot of white stretch marks on her abdomen after giving birth, and she was self-conscious about the effect on her aesthetics, so she wanted to get rid of them. Through the fractional laser treatment with microneedle treatment, while assisting the topical medication after treatment, after a number of treatments, the patient’s abdominal stretch marks can be significantly faded, the treatment effect is gratifying. Basic information] Female, 35 years old [Disease type] Stretch marks [Hospital] Maanshan Seventeen Metallurgical Hospital [Time of consultation] February 2021 [Treatment plan] Fractional laser treatment + microneedle treatment + topical medication (recombinant bovine alkaline fibroblast growth factor gel + fusidic acid cream + cotrimoxazole cream) [Treatment cycle] outpatient comprehensive treatment for 8 months [Treatment effect] Stretch marks are obviously faded. After giving birth a few years ago, Ms. Zhang was left with a lot of stretch marks on her abdomen, which were purplish-red in color at the beginning, and gradually turned white with the passage of time. Although these marks were painless, they always affected her beauty and she wanted to get rid of them, so she went to our clinic. After examination, Ms. Zhang was found to have multiple white atrophic scars on her abdomen, indicating depression, white color, and wax-like luster. Fractional laser treatment with microneedling can gradually stimulate the growth of subcutaneous collagen and minimize stretch marks. However, the above method is not a one-time solution and patients need to undergo multiple treatments, usually at intervals of 2 months. After communicating with the patient, the patient agreed to accept the treatment. Firstly, the patient was given priority to fractional laser treatment, mainly using compound lidocaine cream for 1 hour to reduce the pain of the subsequent laser treatment process. After applying the cream, the patient’s local skin turned slightly white. After 1 hour, the cream was washed off and the local skin was sterilized with 75% alcohol, and then fractional laser treatment was performed. After laser treatment, the treatment is done with ice cold compresses and topical application of recombinant bovine basic fibroblast growth factor gel. After 1 month of fractional laser treatment, the patient came back for a follow-up microneedling treatment. Prior to microneedling, the same compound lidocaine cream was applied to the stretch marks for 1 hour, then the cream was removed and the skin was sterilized, then the microneedle was rolled over the stretch marks 3-5 times. After the microneedling treatment, disinfect the skin for patients and apply recombinant bovine basic fibroblast growth factor gel and fusidic acid cream externally to promote skin repair and prevent infection. After the first fractional laser treatment, there are grid-like red spots at the stretch marks and the redness of the skin at the treatment place, which need a few days to subside completely, during this period, the patient can’t touch the water and apply the ointment on time. 1 month later, the patient will have microneedle treatment again, and there is a mild redness at the scar, and the patient is advised to keep the skin away from water until the redness subsides and the ointment needs to be applied externally as well. After an interval of 2 months, the patient repeated the above operation again. Repeat the operation 2 times, can obviously feel the patient’s stretch marks than before slightly faded, so repeat the treatment 2 times, total 4 times after the treatment, the patient’s abdomen white stretch marks have been significantly faded, the skin condition is almost close to normal skin, the patient is very satisfied with this. After a series of treatments, the patient’s stretch marks have obviously faded and the skin condition is close to normal skin. However, as the patient still need to continue treatment, so still need to pay attention to the following: 1, fractional laser treatment and microneedle treatment, the patient’s skin trauma may appear scabs, the scabs should be allowed to fall off naturally, can not be used to pick, to prevent scarring or secondary infections; 2, the patient in the fractional laser and microneedle treatment, try to avoid strenuous exercise, reduce sweating, and pay attention to go out and do a good job in the sunscreen; 3, patients in the treatment period, should pay attention to try to avoid eating spicy, stimulating food, quit smoking, quit drinking, try to adjust the work and rest, to ensure a good habit of life, which is helpful for the recovery of patients after treatment. Fifth, personal perception Stretch marks is due to the pregnant women’s abdominal skin elastic fiber rupture, caused by atrophic scar, usually painless, but affects the aesthetics. For the treatment of stretch marks, it is difficult to improve the clinic simply by applying drugs, and often need to solve the problem with the help of medical methods, which include fractional laser treatment, micro-needle treatment, gold micro-needle treatment, etc., and generally need multiple treatments to achieve good results. In this article, the patient has adopted fractional laser treatment combined with microneedle treatment, and at the same time with the external application of drugs, the therapeutic effect is more obvious, and the patient’s adherence is stronger, so after 4 times of treatment, the abdominal stretch marks appeared to be significantly faded.