Treatment measures are used according to the different grades of vesicoureteral reflux, which are divided into conservative medical treatment and surgical correction. 1. Grade I and II: Treatment of infection and long-term medication for prevention. Under the guidance of the doctor, choose 1/3 of the therapeutic dose of sensitive antimicrobial agent and take it at bedtime. Furantoin and compound sulfamethoxazole are recommended. SMZCo is available, calculated as SMZ 5-10mg/Kg and TMP 1-2mg/kg, taken at bedtime for more than 1 year. In addition, amoxicillin clavulanate potassium and cephalexin type antimicrobials can be used for oral administration. To prevent infection effectively, urine culture must be done every 3 months; nuclear examination or urinary cystography must be done every year to observe the degree of reflux; venography must be done every 2 years to observe the formation of renal scar. After the reflux disappears, urine culture must still be done every 3-6 months, because reflux can sometimes be intermittent. In addition, we should encourage drinking water, urinate twice before bedtime to reduce the pressure in the bladder, and keep the bowel movement and bowel movement on time. 2.Grade III: The treatment is the same as grade I and II, but reflux should be checked every 6 months and intravenous pyelogram should be done every year. 3.Degree IV and V: Should be surgically corrected after preventive medication.