Allergic purpura can occur at any age, but it is more common in children, the common age of onset is 7 to 14 years old, the male to female ratio is about 1.4:1, the onset has obvious seasonality, the onset of winter and spring is more common, less in summer. Most patients have prodromal symptoms such as general malaise, low-grade fever, malaise and upper respiratory tract infection 1 to 3 weeks before the onset of the disease, with an acute onset and skin purpura as the first symptom, mostly in the distal part of the lower limbs, around the ankles and buttocks and other weight-bearing areas, and rarely in the trunk. The characteristic rash is above the skin, initially as small urticaria or pink papules, which do not fade when pressed. Purpura often occurs repeatedly in batches, symmetrically distributed, with skin edema, bleeding blisters, or even necrosis, forming ulcers. The disease may also manifest early as irregular fever, weakness, loss of appetite, headache, abdominal pain and arthralgia and other non-specific manifestations. The early diagnosis is often difficult when purpura is mild or absent. The treatment of this disease in Chinese medicine is mainly to dispel the evil, including for dispelling wind, cooling blood, invigorating blood, etc.; if the disease is prolonged and recurrent for a long time, it is a deficiency, the treatment is mainly to nourish the deficiency, highlighting the benefit of qi, nourishing liver and kidney, etc.; if the deficiency is mixed with the reality, it should be attacked and nourished at the same time. There is no special treatment for this disease in Western medicine, but Chinese medicine treatment is effective, but if combined with intracranial hemorrhage, renal failure, intussusception and other serious complications should be combined with Chinese and Western medicine rescue treatment. To improve the clinical efficacy, in addition to clinical diagnosis and treatment, we still need to pay attention to the following situations: 1, pay attention to dispel wind and dampness; 2, activate blood circulation and remove blood stasis throughout; 3, harmonize the liver and spleen (gastrointestinal) to collect power. According to Chinese medical theory, the liver is the main organ of blood collection and drainage; the spleen is the main organ of blood control. Allergic purpura is often triggered by external sensation, improper diet, etc. If the spleen and stomach are deficient, it is more likely to lead to this disease, spleen deficiency, dampness and heat agglutination and repeated attacks. The first method is to harmonize the blood, on the basis of which we propose the method of regulating the liver and supporting the spleen (stomach and intestines), and the clinical evidence focuses on softening the liver and harmonizing the blood. Scutellaria baicalensis, Phellodendron, Shanglu; Red peony, Panax ginseng, Dan Shen; Atractylodes macrocephala, Radix Codonopsis pilosulae, Astragalus, etc., together with Xianhecao, Comfrey, Radix et al. For those with long and recurrent illnesses, the method of invigorating the blood and dispelling dampness should be combined with draining the liver and strengthening the spleen. The common prescriptions are Xiao Chai Hu Tang, Gui Shen Tang, Ginseng Ling Bai Zhu San, Si Jun Zi Tang, etc. The allergic purpura is easy to recur, we should actively do the following aspects in the process of treatment of the disease: the acute stage or bleeding a lot, should limit the patient’s activities, bed rest; usually pay attention to living sometimes, work and rest, participate in physical exercise, enhance physical fitness, prevent colds; actively remove the foci of infection, prevention and control of upper respiratory tract infection, control tonsillitis, dental caries, sinusitis, and intestinal parasites and other diseases; actively identify Allergens, avoid eating suspicious food and using suspicious drugs, avoiding foreign protein intake and eating undercooked food. Maintain a positive and optimistic attitude, and keep good communication between doctors and patients to build a wall of disease prevention and treatment together.