Cancer treatment recurrence is a big problem, causes of cancer recurrence and new trends in cancer treatment! We know that there are two major problems in the treatment of cancer, one is the metastasis of cancer and the other is the recurrence of cancer. From the comprehensive observation of various aspects such as etiology, pathology, genetics, development, cellular properties, and response to treatment, the phenomenon of cancer is different from any other human diseases that exist at present. If we still use the same concepts and strategies to understand and dispose of cancer as we do with other human diseases, it is difficult to imagine that we can achieve satisfactory results, which has been fully proved by research and practice over the years. Traditionally, cancer is recognized as an abnormal growth with clear pathophysiological boundaries: cancer cells are a group of cells that have lost growth control and abnormal biological behavior; cancer is not regulated by the normal growth regulation mechanism of the body, grows uncontrollably and destroys normal tissues and organs; heterogeneity, infiltration and metastasis are its basic characteristics; the causes of cancer are complex and diverse, including intrinsic genetic factors, local micro- and environmental factors, immunological factors and external factors. The causes of cancer are complex and diverse, including intrinsic genetic factors, local micro- and immunological factors, and extrinsic biological, physical and chemical inducing and mutagenic factors. Cancer recurrence refers to the reappearance of a controlled cancer in the primary organ, or the invasion of cancer from the primary site into the lymphatic vessels or body cavity and its migration to other sites for continued growth, forming the same type of tumor as the primary tumor. Some cancers may recur months or years after the initial treatment. There are several reasons for the recurrence of cancer: Cancer physique has not changed: Cancer patients have cancer because their body environment has “cancerous physique”, surgery, radiotherapy and chemotherapy have killed the cancer cells, but the regulation mechanism of cell differentiation in the patient’s body has not changed, and the environment for cancer cells to survive has not changed, so new cancer cells will be produced. Therefore, new cancer cells will be produced continuously, and the cancer will recur and metastasize. Incomplete treatment: Surgery can remove cancer cells that have formed a lump, and common radiotherapy and chemotherapy can kill all or part of adult cancer cells, but they are not good for juvenile cancer cells. When the patient’s immune function is low, once juvenile cancer cells wake up from dormant state, they will rapidly fission and mutate to form new adult cancer cells, which is the root cause of cancer metastasis and recurrence. Most of the cancer cells are eliminated by surgery, radiotherapy and chemotherapy, but there are still about 1 million G0 stage (inactive and quiescent) cancer cells in patients’ bodies, which cannot be solved by surgery, radiotherapy and chemotherapy. What’s worse is that some cancer cells have already accumulated in the patient’s body and taken root to form microscopic lesions that cannot be seen by the naked eye or imaging, waiting for an opportunity to grow. These residual cancer cells and microscopic lesions are the culprits of future recurrence. Low immunity: The cells in normal human body keep on metabolizing day and night, and among the new cells formed every day, about millions of cells will undergo genetic mutation, and if a few mutated cells are not restrained by the immune system, they will further malign and form tumor cells. Under normal circumstances, the immune system of the body is always monitoring and destroying these mutated and malignant cells or cancer cells in time, once abnormalities are found, a large number of immune cells will be mobilized to destroy the “foreign molecules”, making it difficult to form a climate. If a person’s immune surveillance function is normal, he or she will be able to snipe carcinogens and cancer cells outside the body and destroy them in the bud. Chemotherapy is a treatment for cancer. Chemotherapy drugs not only kill tumor cells but also normal cells, which reduces the immune function of the patient’s body. To stop cancer recurrence, it is necessary to improve immunity after treatment, rebuild the body’s immune guardian function and repair the body’s regulatory function. Unhealthy lifestyle: After a series of treatment, cancer patients return to life and work and start a new life. Some of them start to smoke, drink and stay up late again, which are not healthy lifestyles. All of these may become factors for cancer recurrence.