Hyperhidrosis mainly refers to patients who sweat more than normal and uncontrollably. It can generally be divided into primary hyperhidrosis and secondary hyperhidrosis. Botox is a good treatment for primary hyperhidrosis. These patients sweat mainly on the palms, armpits, head, face and cheeks. Hyperhidrosis is a common disorder, with epidemiological studies finding a prevalence of about 0.5-1% in young people. Although hyperhidrosis does not pose a great threat to one’s health, it can seriously affect daily life, work and social activities. For example, patients with hyperhidrosis of the hands, usually hands wet all year round, can not engage in paperwork; foot hyperhidrosis patients, the skin of the feet are often impregnated with sweat white, walking will be slippery, especially prone to bacterial infections, the appearance of suffocating odor; as for patients with hyperhidrosis of the armpits. The suffering is even greater, the patient’s shirt is often soaked with sweat, emitting an unpleasant odor, people avoid it. Although hyperhidrosis is not a major disease, but the treatment is very difficult. There are a number of traditional treatments available, such as topical medication. Internal medication, physical therapy, and surgical treatment. Topical medication is usually needed for 2-3 days for topical use. Too many times of topical medication can cause local dryness, mild chafing or severe irritation phenomenon. Internal medications are prone to some side effects, such as sedatives (phenobarbital, isopentobarbital, secobarbital, clomazone, etc.) and small doses of anxiolytics (diazepam, hydroxyzine, doxepin, etc.) are effective for emotional hyperhidrosis. Larger doses of anticholinergics only have the effect of inhibiting sweat secretion and can cause unbearable dry mouth, so they tend to be eliminated. Surgical treatment is more effective for severe patients, but it is time consuming and costly surgery is also more painful. Botox treatment can last for about six months with one injection, and the treatment is less painful. The principle of botulinum toxin treatment for hyperhidrosis is:Sweat mainly comes from sweat glands, and these sweat glands are all innervated by sympathetic nerves, and acetylcholine can make sweat glands secrete, if the body’s acetylcholine secretion is blocked, sweat gland secretion will stop. The endotoxin injection can paralyze the sympathetic nerves in the sweating area, thus blocking or reducing the secretion of acetylcholine, and finally stopping the symptoms of excessive sweating in patients with hyperhidrosis. This treatment is safe and reliable, and complications are rare. Generally, the sweating is reduced within 48-72 hours after Botox injection, and the sweating disappears after 1 week.