Chronic Obstructive Pulmonary Disease (COPD) is a common chronic and progressive respiratory disease. Academician Zhong Nanshan organized nine large general hospitals in China during the “Tenth Five-Year Plan” period to conduct a sample survey of people over 40 years of age in seven regions of China (Beijing, Shanghai, Guangdong, Liaoning, Tianjin, Chongqing and Shaanxi), and found that the total prevalence rate of COPD was 8.2%, with about 43 million people suffering from the disease; the prevalence rate in Tianjin reached 9.64%, with about 1 million people suffering from the disease; the prevalence rate in Tianjin reached 9.64%, with about 1 million people suffering from COPD. The prevalence of COPD in Tianjin was 9.64%, with about 1 million people suffering from the disease. There are gender, urban-rural and regional differences in the prevalence rate, with males having a higher prevalence than females (12.4% vs. 5.1%), but in recent years, with the increase in the prevalence of smoking among females, the prevalence of COPD among female patients has been on the rise year by year. The prevalence increases with age; rural prevalence is higher than urban prevalence (8.8% vs. 7.8%). In China, the incidence of COPD caused by smoking alone is as high as 40.7%. The main clinical manifestations of COPD are chronic cough, sputum, wheezing or shortness of breath after activity, and some early patients can be asymptomatic. Chronic “smoking cough” is the first sign of COPD. Many smokers mistakenly believe that this is a normal reaction to smoking, not realizing that this is the beginning of the disease. With the aggravation of the disease, patients can gradually develop shortness of breath after activities; late development to emphysema, pulmonary heart disease, respiratory failure, a little activity, can appear wheezing, seriously affecting the quality of life of the patients. 2013 Chinese Medical Association Respiratory Disease Branch of the “Chronic Obstructive Pulmonary Disease Diagnostic and Treatment Guidelines” clearly pointed out that COPD is the persistence of airflow limitation can be prevented and treated, airflow limitation is progressive aggravation, mostly associated with the lungs and the lungs. Progressive exacerbation, mostly associated with an abnormal inflammatory response of the lungs to harmful particles and gases.COPD mainly involves the lungs, but can also cause systemic (or extrapulmonary) adverse effects. It is clear that smoking is inextricably linked to the development of COPD. Smoking affects the entire pathophysiologic process of COPD, including occurrence, development, efficacy, regression, and prognosis. Smoking is the first risk factor for the development of COPD. The longer the duration of smoking and the greater the amount of smoking, the higher the prevalence. The prevalence of COPD is more than 10 times higher in smokers than in non-smokers. Twenty-five percent of heavy smokers eventually develop COPD, and 90 percent of COPD patients are smokers. According to statistics, the prevalence of smoking more than 40 cigarettes per day is 75.3%. Smoking significantly increases the cumulative incidence of COPD, 35.5% for continuous smokers and 7.8% for never smokers. Overseas large sample population survey found that there is no significant difference in the incidence of COPD between male and female smokers, and 15-20 years old smokers, women are more likely to develop COPD than men.The occurrence of COPD in addition to positively correlated with the time and number of cigarettes smoked, but also with the types of cigarettes smoked and smoking methods. The risk of COPD in cigar and pipe smokers is only I/3 of that in paper cigarette smokers. There is no significant difference in the risk of COPD between filtered and non-filtered paper cigarettes in male smokers, whereas the incidence of COPD in females is higher in the former than in the latter; the incidence of COPD is not only related to the cumulative amount of cigarettes smoked, but also clearly related to the mode of smoking. The incidence of COPD was higher in smokers who inhaled smoke deeply into the lungs than in those who exhaled smoke after entering the mouth. Smokers have a high rate of abnormal lung function and a rapid annual decline in lung function. Continuous smokers, intermittent quitters, and successful quitters showed decreasing annual decreases in lung function, and surprisingly, those who made several quit attempts but failed to sustain the quit were less impaired compared to continuous smokers. Smoking cessation significantly reduced the incidence of smoking-related cancers and COPD, reduced the degree of lung function decline, and improved exercise tolerance. The rate of lung function impairment can be significantly slowed down in the first year after quitting smoking, and then slowed down year by year, and the incidence of COPD after quitting smoking is delayed by 15-20 years compared with that of non-smokers. More smokers die of COPD than non-smokers. Passive smoking may also contribute to respiratory symptoms as well as COPD. Smoking by women during pregnancy may affect the growth of the fetal lungs and their development in the uterus, and may have an effect on the function of the fetal immune system. The local immune function of the respiratory tract is affected in smokers, making them susceptible to viral and bacterial invasion and thus recurrent respiratory tract infections. Long-term, chronic smoke stimulation, inhalation of harmful particles, repeated infections can easily lead to changes in the normal structure of the respiratory tract, smoking for more than 10 years of people with significant emphysema, 66% of people with bronchial mucous gland cell increase, 80% of people with bronchial inflammation. In short, long-term smoking can form chronic bronchitis, emphysema; while smoking cessation can make chronic bronchitis, emphysema condition is reduced.COPD is a phenomenon of low age, smoking is the main cause. The younger you start smoking, the higher your chance of developing COPD. COPD can be prevented. Smoking cessation is the first and most effective measure to prevent COPD from developing and to reduce the progression of the disease. As smoking gets younger, so does chronic obstructive pulmonary disease. China’s youth smoking rate in recent years there is a rising trend, the age of starting to smoke much earlier, the youth lung capacity continues to decline, will accelerate the occurrence of chronic obstructive pulmonary disease in adulthood. Academician Zhong Nanshan called on the whole society to pay attention to and guide the youth not to smoke, tobacco control, to protect our children not to enter the smoking army, so as to avoid becoming a reserve army of chronic obstructive pulmonary disease. Advise all non-smoking people to never join the ranks of smokers, and at the same time try to help those smokers who make us live in the smoke to quit smoking as soon as possible. Lung function tests should be routinely performed on smokers with or without coughing, sputum, or wheezing. The results may help you see the dangers of tobacco. If you have COPD, regardless of the severity of the disease, you should have regular lung function tests and receive standardized treatment from a respiratory specialist. Whether you are on medication or not, you should quit smoking as soon as possible. No amount of medication can counteract the harmful effects of tobacco. If you are determined to quit smoking, you can trust your respiratory physician to provide you with appropriate assistance, including smoking cessation guidance, psychological counseling, and pharmacological interventions. Your body will benefit from quitting whenever you start. The sooner you quit, the sooner you will benefit. And the benefits will benefit your environment, your family, your friends and future generations.