Tumor liquefaction necrosis after chemotherapy is good, but tumor lysis syndrome may occur. Tumor liquefaction necrosis after chemotherapy suggests that chemotherapy is effective and tumor cells are necrotic; clinically, this situation is common in malignant tumors after the use of sensitive chemotherapeutic drugs, such as lung cancer or metastatic lymph nodes, after chemotherapy, the mass shrinks rapidly, and there are liquid density shadows in the mass after imaging examination. However, liquefaction necrosis after tumor chemotherapy may cause tumor lysis syndrome, metabolic abnormalities such as hyperuricemia, hyperkalemia, hyperphosphatemia, etc.; this is a group of metabolic syndromes caused by chemotherapy leading to massive disintegration of tumor cells, and a large amount of potassium ions, phosphorus ions, and nucleic acids entering the blood circulation, and a few serious cases may also develop acute renal failure, serious cardiac arrhythmia such as ventricular tachycardia and ventricular fibrillation, DIC ( Disseminated intravascular coagulation). If the tumor liquefies and necrotic after chemotherapy, accompanied by nausea and vomiting, diarrhea and anorexia, drowsiness, hematuria, cardiac failure, arrhythmia, convulsions, muscle spasm, etc., we should be alert to tumor lysis syndrome, and timely symptomatic treatment. If you feel unwell, you should go to the hospital and consult your physician.