Runny nose and cough are mostly caused by upper respiratory tract infections, which are the most common acute respiratory infectious diseases that can be caused by cold and climate change, resulting in a decrease in the body’s immunity, which can lead to the occurrence of infections. The pathogens are mostly viral infections, and viral infections are mostly rhinovirus, parainfluenza virus, respiratory syncytial virus, etc.; a few are bacterial infections, including streptococcus and staphylococcus, etc. In general, no special treatment is needed for runny nose and cough, and the course of viral infection is 5-7 days, which can be relieved by itself. If the blood picture is significantly elevated and the percentage of neutrophils is mainly elevated, it is basically clear that it is a bacterial infection, and it is recommended to carry out antibacterial drug treatment under the guidance of a doctor. In conclusion, in general, runny nose and cough are mostly upper respiratory tract infections caused by viruses, and the course of the disease is self-limiting.