Tumor-based prosthesis replacement is a custom-made prosthesis that matches the size of the tumor and the extent of surgical resection, and is the most common technique used in osteosarcoma surgery today. Because most osteosarcomas grow in adjacent joints on the limb, they can be destructive to the joint and affect its function. If you want to restore the function of the joint, you will need a prosthesis for reconstruction. With this method, joint function can be restored in 80 to 90 percent of patients. In the case of a more perfect, standard oncologic prosthesis replacement, some patients have prostheses that last more than 20 years. But for how long the prosthesis will actually last, it is not just the prosthesis itself that matters, but also the patient’s potential for post-operative infection, recurrence, or other complications that can affect the life of the prosthesis.