Tumor patients will have different psychological reactions due to their cultural background, psychological characteristics and different degree of perception of the disease. Tumor patients can go through a series of psychological changes: 1.Shock and denial period: After clear diagnosis, the patient is shocked, manifested as speechless, indifferent, dull-eyed and even fainting. After the diagnosis is made clear, the patient is shocked, which is characterized by speechlessness, indifference, dull eyes and even fainting. This is the protective psychological reaction of the patient in the face of disease stress, but a long duration may lead to delayed treatment. The best care during the shock period is to enhance the interpersonal relationship between the physician and the patient by providing nonverbal companionship, assisting in meeting their physical needs, and giving them a sense of security. Allow some time for acceptance of reality. Do not prevent them from venting their emotions, but be careful to prevent unexpected events. Be consistent in the attitude of the medical and nursing staff during the denial period and answer the patient’s questions affirmatively to reduce the chance of doubt and escape from reality. At the same time, encourage the patient’s family to give him/her emotional support and care in life to make him/her feel safe. 2. Anger period: When the patient has to admit that he/she has cancer, he/she then shows panic, crying, anger, sadness, irritability and dissatisfaction. In order to vent out their inner pain, some patients refuse treatment or get angry at their family members and medical staff, and even appear impulsive behavior. Although this is an adaptive psychological reaction, if it exists for a long time, it will lead to psychological disorders. During this period, the doctor should show a serious and caring attitude in front of the patient, and should not talk and laugh. Before any examination or treatment, a detailed explanation should be given. Also explain to the family the reasons for the patient’s anger so that they can understand the patient’s behavior. And ask other patients to introduce the experience of successful treatment to educate and guide the patient to face the reality. 3. Consultation period: Patients in this period have the strongest desire to live and will pray for a miracle. Patients are receptive to others’ persuasion and have good compliance behavior. Therefore, doctors should strengthen health education for patients and their families, maintain the patient’s self-esteem, respect the patient’s privacy, and enhance the patient’s confidence in the treatment, so as to reduce the adverse consequences of patients seeking medical treatment in an emergency. 4. Depression period: At this stage, although the patient no longer cares about people, things and objects around him, he still pays attention to his illness. Doctors should use appropriate non-verbal communication skills to show concern for the patient, visit regularly, strengthen communication, encourage the patient to vent his emotions and reduce psychological pressure. Encourage their family members to accompany them and prevent accidents from happening. During this period, due to the aggravation of the disease and depression, patients often neglect the handling of personal hygiene. Doctors should encourage patients to maintain the cleanliness and comfort of their bodies and assist in this when necessary. 5. Acceptance period: Some patients, after intense internal struggle, correctly recognize the arrival of the end of life, become calm and usually do not want to talk much. During this period, doctors should respect their wishes, limit visitors for the patient, take the initiative to discover the patient’s needs and try to meet them. When planning care for the patient, the patient’s physiological condition should be taken into account, and it is best to focus the physician so as not to increase the patient’s suffering. The above psychological changes can occur simultaneously or repeatedly, and there are great differences in the staging of psychological changes in people with different psychological characteristics, in addition to the duration and order of appearance of each stage. Therefore, doctors should always pay attention to the psychological reactions of patients and give appropriate care.