Hypertension drug side effects are as follows: 1, diuretics: divided into thiazide diuretics, tab diuretics, potassium-preserving diuretics, tab diuretics prone to low potassium and sodium, etc., potassium-preserving diuretics lead to an increase in blood potassium, aggravating the condition; 2, calcium antagonists: light side effects, prone to mild swelling of the ankle joints of the lower extremities, appropriate combination of diuretics, can be improved more quickly; 3, beta-blockers: affect the conduction of the heart. It can affect glucose metabolism and lipid metabolism and aggravate heart failure, acute asthma or chronic obstructive pulmonary disease; 4. α-blockers: less frequently used, prone to postural hypotension, requiring attention to blood pressure fluctuations; 5. Angiotensin-converting enzyme inhibitors: the current mainstream anti-hypertensive drugs, often due to severe dry cough or increase the level of bradykinin in the body, cough; 6. Angiotensin II receptor antagonists: safer and have small side effects.