Acute epiglottitis is a common infectious disease in laryngology. With epiglottitis, the epiglottis is congested and swollen, and the throat is severely painful. It can be accompanied by uncomfortable symptoms such as difficulty in breathing, difficulty in swallowing, and even choking in severe cases. If patients suspect they have acute epiglottitis, they can be diagnosed through physical examination, laboratory tests, laryngoscopy and imaging tests to clarify whether they have the disease.1. Physical examination: Patients may show symptoms such as flushing, excitement, painful expression, etc. In severe cases, the respiratory rate is accelerated and there are depressions on the body surface when breathing. When the disease is acute, there will be severe sore throat, painful swallowing, saliva spillage, coughing and sputum, etc. In severe cases, laryngeal obstruction and asphyxia may occur; 2. Laboratory tests: routine blood tests will have the results of elevated white blood cells, neutrophils or eosinophils, suggesting infectious inflammation or allergic reactions, pathogen culture can see pathogenic bacteria, immunological tests can find antibodies to specific pathogens; 3. Laryngoscopy. In the early stage of the lesion, the epiglottis will be swollen and thickened, pale white or cherry red, and in severe cases, enlarged and spherical, in the late stage of the lesion, the epiglottis will form a limited abscess, which can be seen as a local elevation with yellow pus spots, pus heads, overflowing pus or ulcers; 4, imaging: lateral X-ray of the larynx can show that the patient’s epiglottis is swollen and enlarged, and the shadow of the laryngopharyngeal airway can be seen to shrink with clear boundaries. The laryngopharyngeal cavity is narrowed. The laryngopharyngeal respiratory tract epiglottitis is a serious infection, after the diagnosis need to actively symptomatic anti-inflammatory treatment, can apply cephalosporin antibiotics and glucocorticoid drug therapy, such as local abscess formation, feasible surgical incision to drain the pus, with severe respiratory distress should be timely tracheotomy to open the airway.