Genital herpes, acute gonorrhea, sexual lymphogranuloma, etc. will cause groin pain; the main manifestations are swollen lymph nodes in the groin, pain, and so on. 1. Genital herpes: the acute onset of genital herpes can lead to inguinal lymph node swelling and groin pain, especially primary genital herpes groin pain symptoms are more obvious. 2. Acute gonorrhea: acute gonorrhea is caused by infection with gonococcus bacteria causing urethral irritation and swelling of inguinal lymph nodes, resulting in pain in the groin area, which can be completely cured by injection of ceftriaxone or macrolide treatment. 3. Sexual lymphogranuloma: the most typical clinical symptom of sexual lymphogranuloma is enlarged inguinal lymph nodes, and may be accompanied by pus and other symptoms, manifested as pain in the groin, if the enlarged lymph nodes rupture. If the enlarged lymph node breaks down, it will discharge yellow or purulent bloody secretions. This leads to the formation of fistulas, such as anal fistulas. In addition to STDs, there are other diseases that may also cause groin pain, and need to go to the hospital in time, to clarify the cause of the cause of treatment.