Hand sweating is a disorder caused by excessive secretion of sweat glands due to sympathetic hyperexcitation. Whether it is hot summer or cold winter, the hands are wet and cold, more serious in winter, some severe hand sweating can lead to hand peeling, blisters and eczema. Although hand sweating does not affect health, but serious often cause patients in learning, work, life or social inconvenience, affecting the patient’s self-confidence and quality of life, common patient psychological stress, mental anxiety and even depression, etc.. Because the main control of hand sweat secretion is in the thoracic sympathetic nerve, so thoracoscopic bilateral thoracic sympathectomy is the first choice for the treatment of hand sweat, a small hole of 0.3 to 0.5 cm in diameter is made in each side of the armpit, and the sympathetic nerve controlling hand sweat can be cut under thoracoscopic surveillance. The first day after surgery, the patient can be discharged in the morning, and the satisfaction rate of surgical treatment is over 98%.