Todd paresis: In general, there is no significant change in limb function after a seizure, but there are some patients with partial motor epilepsy who have a seizure in which the twitching limb cannot move for several minutes to hours and then returns to normal. We refer to this temporary paralysis after a seizure as Todd’s palsy, also known as Todd’s palsy. When a patient with epilepsy develops Todd paresis, it often suggests an organic lesion in the patient’s brain, and further tests must be done to clarify the cause. How is Todd’s palsy checked? Todd’s palsy is a neurological abnormality that occurs in people with epilepsy, which is a brief paralysis that occurs when epilepsy occurs. The palsy can be localized or generalized, but usually occurs on only one side of the body. It most commonly follows a generalized tonic-clonic seizure (grand mal) and may last for several hours or occasionally for several days after the seizure has passed. The etiology of the condition is unclear, but there are two hypotheses. One is the attrition theory, in which depletion of the motor cortex leads to prolonged hyperpolarization of neurons. The second is a transient motor fiber inactivation due to NMDA receptor activation. Since the paralysis disappears quickly, the treatment of the disease is symptomatic and supportive. The prognosis of the disease is related to the degree of epilepsy. The most significant aspect of the disease is the differential diagnosis with stroke. In the acute phase, certain strokes can trigger a limited seizure. And if Todd’s paralysis occurs in such a context, the patient’s neurological condition is often overestimated, thus leading to medical interventions such as thrombolytic therapy errors. For such reasons, thrombolytic therapy is generally considered a relative contraindication for seizures that occur in the acute phase of stroke, especially if evidence of cerebrovascular infarction is still lacking before vascular imaging. Thrombolytic therapy is contraindicated in cases where the diagnosis is not clear. Antiepileptic, anticoagulation, vasodilatation, brain cell nutrition, free radical scavenging, and acupuncture are recommended first, while further investigations should be done as soon as possible.