In recent years, the Mild Stimulation ovulation protocol has become increasingly sophisticated and popular as the medical understanding of ovulation promotion techniques has improved, the efficiency of ultra-ovulatory treatment has been repeatedly validated and reflected upon, and the average age of the IVF patient population has increased. So, what exactly is a microstimulation ovulation protocol (ovarian microstimulation protocol)? Ovarian microstimulation protocols, as opposed to traditional controlled ovulation protocols (COH). Formally, any ovarian stimulation protocol that is likely to be mild and does not involve down-regulation or up-regulation of the pituitary gland is considered a microstimulation protocol. Specifically, at a minimum, these should include: low-dose gonadotropin ovulation promotion late stimulation regimens clomiphene regimens aromatase inhibitor (letrozole) regimens pituitary gonadotropin-releasing hormone inhibitor (GnRH-Ant) regimens From the point of view of the ovulation regimen developer, any regimen that does not want to deeply stimulate the ovaries and wants to obtain a limited number of eggs (<7) should be referred to as a microstimulation regimen; from the point of view of In terms of ovulation results, any regimen that actually obtains a small number of eggs (<7) should be called microstimulation ovulation. Each of these criteria has validity, but none of them alone can fully cover the full meaning of a microstimulation protocol. For example, there are patients who receive a very strict formal letrozole regimen for ovulation, and as a result, they get 20 to 30 eggs with dense follicles throughout the ovary, even raising concerns about whether ovarian hyperstimulation may be occurring. Can such a regimen be called "microstimulation", at least for this patient? In some older patients, with declining ovarian function, only a few eggs are obtained after deep stimulation of the ovaries with massive amounts of gonadotropins. So, can we assume that this is a "microstimulation" ovulation because the number of eggs obtained is less than 7? I believe that a true ovarian microstimulation protocol must be considered on an individual basis. It must be formally unregulated by down-regulation or up-regulation of pituitary function (e.g. classical long and short protocols), and it must be within the range of <7 eggs, both in terms of the original intention of the protocol maker and in terms of the final result of egg retrieval. A microstimulation protocol that is strictly valid for one patient may not be called "microstimulation" if it is transferred to another patient in its original form.