With the popularization of computers and the aging of the population, the trend of patients with low back pain is increasing. The diseases causing low back pain are clinically focused on lumbar back myofasciitis, lumbar discogenic pain, lumbar spine small joint disorder and lumbar disc herniation. Myofasciitis of the low back is a series of clinical symptoms caused by edema, exudation and fibrous changes in the myofascia and muscle tissue of the low back due to cold, humidity and chronic strain. The pain is characterized by morning pain, light during the day and heavy in the evening, and can be triggered by prolonged inactivity or excessive activity. It can be treated by closure therapy to relieve the symptoms in time. There are two types of discogenic low back pain: low back pain caused by internal disc disruption (IDD) and low back pain caused by internal endplate disruption (IED). Both types of discogenic low back pain are clinically diagnosed by lumbar discography. Minimally invasive interventional treatment can effectively relieve pain. Percutaneous puncture ozone myeloablation and thermal coagulation are one kind of minimally invasive interventional treatment, which has been widely carried out clinically and has the characteristics of no bleeding, little injury, quick recovery and high safety, which can remove the compression on nerves and achieve the purpose of treating low back pain. Patients with disorders of the small joints of the lumbar spine tend to lie on their sides in flexion, unable to straighten their waists, afraid to move, and afraid of being touched by others, and are often misdiagnosed as acute lumbar muscle sprain. In fact, the exact diagnosis should be the lumbar joint synovial imbrication, or called lumbar posterior joint disorder, commonly known as your small joint disorder. If not released in time, it will produce chronic severe lumbar pain and arthritis. The symptoms can be relieved by manipulation and closure therapy to get an immediate effect. Lumbar disc herniation: its incidence is increasing year by year, and there is a trend of younger patients. Treatment methods mainly focus on conservative treatment, minimally invasive treatment and surgery. For patients with unsatisfactory results of conservative treatment, minimally invasive treatment is an effective means. Minimally invasive treatment includes minimally invasive interventional therapy, foraminoscopy, discoscopy and micro-minimally invasive techniques, which can precisely release the compression and treat it completely.