Cancer pain is a sensation caused by the transmission of information to the nerve center about the need to repair or regulate the pain site, alias, cancer pain, advanced cancer pain, and is one of the main causes of pain in patients with advanced cancer. Among the pain patients, 50% to 80% of pain is not effectively controlled for various reasons. Cancer pain is usually treated mainly by medication, and surgical treatment often needs to be considered in the context of the patient’s overall physical condition and survival. After the causes of pain are clearly identified and treated, the analgesic effect and the degree of pain relief must be evaluated in order to formulate the future treatment plan and drug dosage. 1. Analgesic treatment (1) Principles of drug treatment for cancer pain: ① Take the drug orally as much as possible to facilitate long-term use, which can reduce dependence and addiction. (2) Give the drug regularly and on time, rather than giving it when pain occurs. (3) Give medication according to the step, according to the “three step therapy” recommended by WHO for cancer pain. ④The medication should be individualized. ⑤ Pay attention to the use of anxiolytic, antidepressant and hormonal drugs, which can improve the effect of analgesic treatment. (2) The “three-step therapy” of cancer pain medication: ① First step – non-opioid analgesics: used for patients with mild cancer pain, the main drugs are aspirin, acetaminophen (paracetamol), etc. Adjuvant drugs can be applied as appropriate. The main drugs include codeine, which is generally recommended to be used in combination with the first-tier drugs because the mechanism of action of the two types of drugs is different, with the first-tier drugs acting mainly on the peripheral nervous system and the second-tier drugs acting mainly on the central nervous system. The combination of the two drugs can enhance the analgesic effect. Adjuvant drugs can also be used as needed. The main drug is morphine, and adjuvant drugs can also be used as appropriate. Surgical treatment (1) posterior median posterior cord dissection (PMM): animal experiments and cadaveric neuroanatomy have confirmed that most of the upstream conduction pathways of visceral nociception are upstream through the dorsal column of the spinal cord, especially for the conduction of visceral nociception in the pelvis and lower abdomen, the role of the dorsal column of the spinal cord even exceeds that of the thalamic tract of the spinal cord. In 1997, Nauta et al. were the first to report a case of thoracic 8 PMM for the treatment of advanced recalcitrant pelvic and lower abdominal visceral pain in cervical cancer with definite efficacy. 1999, Becker et al. in Germany also reported a case of lung cancer with epigastric and mid-abdominal pain after surgery, and thoracic 4 PMM significantly relieved the pain symptoms. 2000, KimYS et al. in Korea reported successful 8 cases of thoracic 1 to 2 segmental PMM were administered, all of which were abdominal visceral pain caused by gastric cancer, and the pain relief effect was positive. (2) Spinal cord pain relief surgery: According to the different sites and characteristics of cancerous visceral pain, posterior spinal nerve root dissection, anterolateral spinal cord bundle dissection and anterior joint spinal cord dissection are considered. Since surgery destroys the spinal cord structure and may cause other complications such as motor or sensory disorders, it should be carefully selected in consideration of the overall functional status of the patient. In order to improve the survival quality of cancer pain patients and to reduce or even relieve pain, WHO has developed the cancer pain relief program, which is a three-stage drug gradient pain relief method. At present, although the efficacy of this program is relatively accurate, the long-term use of analgesics has great toxic side effects, addiction and dependence, and is limited by patients’ tolerance, resulting in poor pain relief for some patients. We summarize the pathogenesis of pain as qi stagnation, blood stasis, phlegm turbidity, heat toxicity, deficiency, etc. For cancer pain caused by different etiologies, we adopt different external treatment methods, and apply the medicine on the painful part of cancer or navel. The effective ingredients are absorbed through the skin and mucous membrane through transdermal absorption. It can be applied to the painful area or the local part of the lump or the navel, so that the drug can act directly on the painful area or the meridian circulation, which can have an immediate pain relief effect on cancer pain, and the pain relief lasts for a long time and has a definite efficacy.