The current strategy, which tends to be consistent at home and abroad, is summarized as follows: in the early stage, non-surgical treatment centering on the maintenance of organ function is adopted, aseptic necrosis is treated non-surgically as far as possible, and surgical treatment is adopted after the emergence of necrotic infection. 1, non-surgical treatment The initial stage of the disease should be supervised and treated in ICU, and the principles are to replenish body fluids, maintain water-electrolyte balance, energy support, and prevent the emergence of local and systemic complications. Monitoring includes: vital signs, Sao2, urine volume/2h, electrolytes, calcium, magnesium, phosphorus, muscle liver, urea nitrogen/8h, blood count, arterial blood gas, chest X-ray. Early management includes: fluid resuscitation, oxygen therapy, fasting, analgesia, H2 receptor antagonists, gastrointestinal decompression, etc. The focus is on the maintenance of organ function. Special treatment includes: enzyme inhibiting agents, anti-pancreatic secretagogues, platelet activating factor antagonists: Leipafant, prophylactic use of antimicrobial antibiotics: in the use of antimicrobial antibiotics, carbene antibiotics are recommended for those with pancreatic necrosis. Prevention and control of early complications ARDS, acute renal failure, shock, DIC, metabolic encephalopathy. In addition to this several explorations in the non-surgical treatment of SAP are currently being carried out around the world, including continuous hemofiltration and peritoneal lavage. However, its role has yet to be confirmed by further studies. 2. Surgical treatment includes: 2.1. Pancreatic necrotic tissue removal is performed by blunt or with suction, removing necrotic tissue, placing drains in the pancreatic bed, small omental sac, bilateral posterior colon, etc., and continuous local irrigation and drainage. From the clinical data, the operation of pancreatic necrotic tissue removal is more reasonable, simple and easy to perform, less damaging, less complications and lower mortality. 2.2. Open abdominal tamponade: The pathological changes of severe acute pancreatitis are progressive, and there is no procedure that can completely treat this disease at once. The principle is to keep it simple, facilitate re-drug changes and prevent mixed infections.