Acute pancreatitis is a common emergency and serious disease of the digestive system. With the improvement of people’s living standards and the accelerated pace of life, the incidence of pancreatitis is increasing year by year, and according to the condition, it can be divided into mild pancreatitis and severe pancreatitis. Severe pancreatitis is often complicated by respiratory distress syndrome, acute renal failure, upper gastrointestinal bleeding, pancreatic abscess and other serious complications, with a death rate of 30%-50%, which is a disease that seriously affects people’s health. Yang Guohong, Department of Splenic, Gastrointestinal and Hepatobiliary Diseases, The First Affiliated Hospital of Henan College of Traditional Chinese Medicine, causes many causes of acute pancreatitis, and according to data, more than half of the pancreatitis is caused by gallstone disease in China, especially microscopic stones. In addition, overeating, excessive alcohol consumption and hyperlipidemia are also common causes of pancreatitis. The clinical manifestations of acute pancreatitis onset are mainly abdominal pain and distension, which are often misdiagnosed as acute gastritis, cholecystitis, intestinal obstruction and gallstone disease, and early diagnosis is very important for the treatment of acute pancreatitis, therefore, if there is dietary disorders or sudden onset of acute abdominal pain, you should come to the hospital, and the main tests that need to be done are serum amylase and lipase, abdominal pancreatic ultrasound and CT. in the past few years We have met more than once patients who were misdiagnosed as acute gastroenteritis, intestinal obstruction, cholecystitis, etc. Once the condition is misdiagnosed, it is easy to miss the time of treatment, leading to aggravation and evolution of the condition. For example, we have admitted such a patient, that is, three years ago during the Spring Festival, the patient several family and friends get together, excessive drinking and eating meat, resulting in abdominal pain, had been treated in a city hospital according to acute gastroenteritis, three days can not eat, nausea and vomiting, abdominal pain and bloating continues unabated, bedridden, came to our hospital for diagnosis has been severe pancreatitis. In acute mild pancreatitis, the pancreatic tissue is mostly edematous and there is no tissue necrosis, so treatment is relatively easy and good results can be obtained by giving fluid supplementation. Acute severe pancreatitis, on the other hand, is characterized by rapid changes in the condition, a dangerous prognosis and a high mortality rate. A large number of clinical studies and experimental results show that the occurrence of acute severe pancreatitis is a response to systemic inflammation, the severity of which basically depends on the severity of the pancreas itself and the extent of peripancreatic necrosis and secondary infection, and the inflammatory mediators released by the inflammation can cause tissue damage and affect the normal function of all systems, and even develop into multi-organ failure. Especially, the necrotic material infiltrates into the abdominal cavity, which can make the intestinal wall congested, edematous and dilated, and the intestinal peristalsis slows down, which is conducive to the propagation and displacement of intestinal bacteria. In recent years, the use of combined Chinese and Western medicine in the treatment of severe pancreatitis has made great progress, with significantly improved clinical efficacy and a significant decrease in the rate of surgery and death. Therefore, the treatment focuses on early treatment, rapid relief of abdominal pain symptoms and prevention of complications. Acute pancreatitis is considered by Chinese medicine to be within the scope of “spleen and heart pain” and “abdominal pain”. In the process of disease development, Qi stagnation and blood stasis in the internal organs and dampness and heat accumulation are important links, and in serious cases, it leads to the failure of internal organs, imbalance of yin and yang, change of evidence, and difficulty in treatment, so the treatment of this disease in Chinese medicine focuses on the early passage of internal organs and diarrhea, clearing heat and dampness, activating blood circulation, resolving blood stasis, detoxifying and dispersing knots, adjusting the function of internal organs, and stopping the development of the disease, which has an important role in the treatment of pancreatitis. Our department has conducted clinical research on acute pancreatitis, focusing on the combination of Chinese and Western medicine, based on fasting, rehydration, anti-inflammation and inhibition of pancreatic enzymes, applying Chinese medicine gavage, enema, external application, intravenous infusion and acupuncture. The clinical effect proves that after applying Chinese medicine, the patient’s abdominal pain and bloating relief time is shortened and the exhaustion and defecation increase, which is conducive to the elimination of toxins in the intestinal tract, avoiding secondary infections and reducing complications. Reduce complications, restore the balance of the body’s internal environment, so that the disease can be healed and complications can be reduced. Shorten the hospitalization days and reduce the hospitalization cost of patients. In addition, as the number of patients with pancreatitis increases, we also treat many special types of pancreatitis, such as pancreatitis caused by hyperlipidemia, autoimmune pancreatitis, chronic pancreatitis, pancreatic pseudocysts, etc. All patients can be cured and discharged after treatment with Chinese medicine. In the past 5 years, our department has treated more than 300 cases of acute pancreatitis, including more than 100 severe cases, but the patients treated with the combination of Chinese and Western medicine are much lower than the data reported in the literature in terms of symptom relief and complications, which shows the superiority of the combination of Chinese and Western medicine.