A strong cough at 12 pm is seen clinically for many reasons, from respiratory diseases to infectious factors, such as wheezing bronchitis, pneumonia, bronchiectasis, chronic obstructive pulmonary emphysema, and other co-infections. Increased inflammatory secretions in the airways, which can reflux into the airways or throat at 12 o’clock at night, cause coughing. In addition, non-infectious respiratory diseases, such as cough variant asthma, which is a special type of bronchial asthma, are stimulated by allergens, and at night, especially after lying down, there is wheezing, shortness of breath, irritating cough, and contraction and spasm of the smooth muscles of the airways that aggravate the symptoms of coughing. In cardiovascular diseases, various causes of left heart failure lead to massive fluid leakage from the pulmonary mucosa, causing pulmonary edema, and the patient may cough up pink foamy sputum and have symptoms of telangiectatic breathing.